Picoplus afm instrument

Manufactured by Agilent Technologies

The PicoPlus AFM instrument is a powerful atomic force microscope designed for high-resolution imaging and analysis of surface topography. It utilizes a sensitive cantilever-based detection system to measure the interactions between a sharp probe and the sample surface, providing nanometer-scale resolution. The PicoPlus is a versatile tool for a wide range of applications in materials science, nanotechnology, and life sciences.

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Lab products found in correlation

Picospm 2 controller, by Agilent Technologies (2 mentions) Nsc36 no al cantilevers, by MikroMasch (2 mentions)

Close spelling variants of this product

PicoPlus AFM PicoPlus

2 protocols using picoplus afm instrument

AFM Imaging of Samples on Mica

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A PicoPlus AFM instrument with a PicoSPM II controller from Molecular Imaging (Agilent) was used for the AFM imaging studies. Images were acquired at room temperature in air using the AC mode with NSC36/no Al cantilevers (Mikromasch, with force constants varying from 0.6 to 2 N m⁻¹). For each imaging experiment, an aliquot of the corresponding solutions was deposited onto freshly cleaved mica and left to dry without rinsing.

Ouberai M.M., Dos Santos A.L., Kinna S., Madalli S., Hornigold D.C., Baker D., Naylor J., Sheldrake L., Corkill D.J., Hood J., Vicini P., Uddin S., Bishop S., Varley P.G, & Welland M.E. (2017). Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly. Nature Communications, 8, 1026.

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Atomic Force Microscopy of Samples

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A PicoPlus AFM instrument with a PicoSPM II controller from Molecular Imaging (Agilent) was used for the AFM imaging studies. Images were acquired at room temperature in air using the AC mode with NSC36/no Al cantilevers (Mikromasch, with force constants varying from 0.6 to 2 N m^-1). For each imaging experiment, an aliquot of the corresponding solutions was deposited onto freshly cleaved mica and left to dry without rinsing.

Ouberai M.M., Gomes Dos Santos A.L., Kinna S., Hornigold D.C., Baker D., Naylor J., Liang L., Corkill D.J, & Welland M.E. (2023). Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake. Frontiers in Endocrinology, 14, 1217021.

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