Deuterated chloroform cdcl3

Bisphenol AF (>98%), 4,4′-oxydianiline (>98%), and 1-(2-furyl)methylamine (99%) were purchased from TCI America (Portland, OR, USA). Paraformaldehyde (>95%), tetrahydrofuran (≥99.9%), and TLC Silica gel 60 F254 (100 glass plates, 2.5 cm × 7.5 cm) were obtained from Sigma Aldrich (Burlington, MA, USA). Chloroform and sodium hydroxide (NaOH) were received from Fisher Scientific Company (Waltham, MA, USA). Deuterated Chloroform (CDCl3) (99.8%) was purchased from Cambridge Isotope Laboratories., Inc. (Tewksbury, MA, USA). Glycidyl isobutyl POSS (EP0418) was purchased from Hybrid Plastics Inc. (Hattiesburg, MS, USA). Woven 3M Nextel 312 ceramic fabric (Style AF-40, 5 harness satin weave, 1800 denier, heat cleaned) was purchased from Bristal Metal Products, Inc. (Westlake, OH, USA). All chemicals were used as received.

D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS₁₀₀₀), ε-Caprolactone (97%), and stannous octoate were purchased from Sigma-Aldrich (St. Louis, MO, USA). D-α-Tocopherol polyethylene glycol 2000 succinate (TPGS₂₀₀₀), D-α-Tocopherol polyethylene glycol 3500 succinate (TPGS₃₅₀₀), and D-α-Tocopherol polyethylene glycol 5000 succinate (TPGS₅₀₀₀) were obtained from Wuhan Jason Biotech Co., Ltd. (Wuhan, Hubei, China). Paclitaxel (99%) was purchased from Shaanxi Sciphar Biotechnology Co., Ltd. (Xianyang, Shijiyiuan, China). Ebetaxel^® (300 mg/50 mL, concentrate for infusion; Ebewe Pharma, Unterach, Austria; Lot# HN5538), a generic of Taxol^® approved by the US FDA, was obtained from King Khalid University Hospital Pharmacy (Riyadh, Saudi Arabia). Deuterated chloroform (CDCl₃, 99.8%) was purchased from Cambridge Isotope Laboratories Inc. (Tewksbury, MA, USA). Polysorbate 80 (Tween 80) was purchased from Bio Basic Inc. (Markham, ON, Canada). Potassium dihydrogen orthophosphate, dipotassium hydrogen orthophosphate, and potassium chloride were obtained from BDH Chemical Ltd. (Poole, England). Acetonitrile, methanol, and water were all HPLC grade and were purchased from BDH Chemical Ltd. (Poole, England). All other chemicals were reagent grade.

Sodium alginate was extracted from the brown algae Saccharina latissima using a cyclic fractionation process in which diluted sodium citrate was used in 18 sequential extractions from the same biomass [4 (link)]. The alginate fraction used in this work was recovered, by acid precipitation followed by centrifugation, from the 16th extraction cycle. The algae were cultivated on the Swedish west coast and harvested on 17 May 2016, from a cultivation site at the Sven Lovén Centre for Marine Science (University of Gothenburg). The precise extraction protocol is described in a previous work [8 (link)]. Commercial sodium alginate, sodium hydroxide (≥97% ACS reagent, CAS: 9005-38-3), maleic anhydride (MA) (≥99.0% puriss), n-dodecanol (DD) (≥98%, reagent grade), calcium chloride dihydrate (CaCl₂) (≥99% ACS reagent), sodium oxalate (≥99.5% ACS reagent), and phytic acid (≥90% phosphorus basis) were purchased from Sigma-Aldrich, Sweden. Deuterated chloroform (CDCl₃) (99.96%) was purchased from Cambridge Isotope Laboratories, U.S.A. Linseed oil was purchased from Slöjdetaljer, Sweden, and produced by Eskil Åkerberg AB, Staffanstorp, Sweden.