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Mip1α

Manufactured by Mesoscale
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Sourced in United States

MIP1α is a laboratory product that functions as a chemokine. It is involved in the recruitment and activation of specific immune cells. The core function of MIP1α is to mediate inflammatory and immune responses.

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Lab products found in correlation

Mcp 1, by Mesoscale (2 mentions) Vascular endothelial growth factor (vegf), by R&D Systems (2 mentions)

2 protocols using mip1α

1

Quantifying Inflammatory and Angiogenic Biomarkers

Check if the same lab product or an alternative is used in the 5 most similar protocols
Inflammatory biomarkers and angiogenic biomarkers were quantified by ELISA. Custom multiplex assays were performed to measure mouse pro-inflammatory markers (IL-1β, IL-6, KC, IL-10, TNFa) and cytokines (MCP-1, MIP1α) (MesoScale Discovery, Gaithersburg, USA) in serum samples (diluted two-fold and four-fold, respectively). Mean reported intra- and inter-assay coefficients of variation for these assays are all <10% and <12%, respectively. Angiogenic markers (VCAM, VEGF) (R&D Systems Inc, Minneapolis, USA) were measured in serum samples and fracture callus tissue lysates (diluted 50-fold and 20-fold for measurement of VCAM, respectively and diluted fivefold for measurement of VEGF). Mean reported intra- and inter-assay coefficients of variation for these assays are all <10% and <12%, respectively.
Huang R., Vi L., Zong X, & Baht G.S. (2020). Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(10), 13521-13532.
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2

Quantifying Inflammatory and Angiogenic Biomarkers

Check if the same lab product or an alternative is used in the 5 most similar protocols
Inflammatory biomarkers and angiogenic biomarkers were quantified by ELISA. Custom multiplex assays were performed to measure mouse pro-inflammatory markers (IL-1β, IL-6, KC, IL-10, TNFa) and cytokines (MCP-1, MIP1α) (MesoScale Discovery, Gaithersburg, USA) in serum samples (diluted two-fold and four-fold, respectively). Mean reported intra- and inter-assay coefficients of variation for these assays are all <10% and <12%, respectively. Angiogenic markers (VCAM, VEGF) (R&D Systems Inc, Minneapolis, USA) were measured in serum samples and fracture callus tissue lysates (diluted 50-fold and 20-fold for measurement of VCAM, respectively and diluted fivefold for measurement of VEGF). Mean reported intra- and inter-assay coefficients of variation for these assays are all <10% and <12%, respectively.
Huang R., Vi L., Zong X, & Baht G.S. (2020). Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(10), 13521-13532.
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