All patients underwent a skin-sparing or skin-reducing mastectomy with immediate prepectoral implant reconstruction. The incision depended on the patient’s breast volume and degree of ptosis and included inframammary fold, Wise pattern, and periareolar incisions. The prepectoral implant was supported by one of a variety of ADMs including Strattice (Allergan, Ireland), Artia (Allergan, Ireland), and Surgimend (Integra LifeSciences) sutured to the anterior chest wall with 3-0 PDS (Polydioxanone) (Ethicon, UK). All incisions were closed with absorbable 3-0 Monocryl sutures (Ethicon, UK) for the dermis and 4-0 Monocryl for the subcuticular skin closure. The wounds were then glued with Dermabond skin adhesive (Ethicon, UK). NPWT was applied according to the manufacturer’s instructions (PICO, Smith & Nephew, UK), with size of dressing matched to wound size. Standard dressings were an Opsite (Smith & Nephew, UK) transparent waterproof dressing with an absorbent pad. Figure 1 shows the application of the PICO dressing in theatre.
Strattice
Manufactured by Abbvie
Sourced in Ireland
Strattice is a biologic tissue matrix derived from porcine dermis. It is designed to serve as a surgical mesh to provide support and reinforcement to damaged or weakened tissue.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using strattice
1
Immediate Prepectoral Implant Reconstruction
2
Immediate Breast Reconstruction after Mastectomy
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Fifteen female (age range 18–80 years) healthy, non-pregnant study participants were enrolled. Inclusion criteria were defined as follows: history of BC, carcinoma in situ on one or both breasts and/or known genetic BRCA I or BRCA II mutation and planned NSM or SSM, and following IBR with definite implants. Exclusion criteria were defined as follows: BC diagnosis with the contraindication for NSM or SSM (e.g., inflammatory carcinoma), use of tissue expanders; diabetes mellitus type 1 and 2, nicotine abuse, inability to fully comprehend study procedures or to provide written informed consent. The reconstruction was performed in dual plane technique using anatomical silicone implants (Mentor Deutschland GmbH, Munich, Germany), placed subpectorally. The acellular dermal matrix Strattice™ (Allergan, Dublin, Ireland) was used for implant stabilization and affixed to the musculus pectoralis major as well as in the inframammary fold. Postoperative follow-up visits were uniformly scheduled at 1, 2 and 6 weeks postoperative.
Additional patient-related, (age, Body-Mass-Index (BMI), body temperature), surgery-related (incision type and position, implant size, surgery duration) and environment-related data (room temperature) were acquired.
Additional patient-related, (age, Body-Mass-Index (BMI), body temperature), surgery-related (incision type and position, implant size, surgery duration) and environment-related data (room temperature) were acquired.
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