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P tau181

Manufactured by Quanterix
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Sourced in United States

The P-tau181 is a laboratory equipment product developed by Quanterix. It is designed to measure the levels of phosphorylated tau protein (p-tau181) in biological samples.

Automatically generated - may contain errors

Lab products found in correlation

Simoa ptau181 advantage kit, by Quanterix (1 mentions) Neurology 4 plex e, by Quanterix (1 mentions) Simoa hd x analyzer, by Quanterix (1 mentions)

Close spelling variants of this product

Simoa p-tau181 P-tau181 Advantage V2 kit P-Tau181 V2 kit

2 protocols using p tau181

1

Multiplexed Neurodegenerative Biomarker Assay

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Human Simoa Neurology 3-Plex A (N3PA) Advantage kit was carried out to evaluate levels of total-tau, amyloid-β40, and amyloid-β42, while Simoa p-tau181 Advantage kit was used to measure p-tau181 (Quanterix, Billerica, MA, USA). Each sample was measured in duplicate and two control samples added to each plate were used for each analyte. All measurements were performed at Quanterix on a single molecule assay (Simoa) biomarkers detection system.
Piscopo P., Manzini V., Rivabene R., Crestini A., Le Pera L., Pizzi E., Veroni C., Talarico G., Peconi M., Castellano A.E., D’Alessio C., Bruno G., Corbo M., Vanacore N, & Lacorte E. (2022). A Plasma Circular RNA Profile Differentiates Subjects with Alzheimer’s Disease and Mild Cognitive Impairment from Healthy Controls. International Journal of Molecular Sciences, 23(21), 13232.
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2

Plasma Biomarkers for Neurodegeneration

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Aβ40, Aβ42, glial fibrillary acidic protein (GFAP), Nf-L, and P-Tau181 were measured in EDTA plasma using the respective commercially available kits; Neurology 4-Plex E and P-Tau181 (Quanterix©, Billerica, MA, USA) by Single Molecule Array (SIMOA®) HD-X Analyzer. The analyses were performed according to the manufacturer’s instructions. In addition, the manufacturer’s commercial controls were applied for quality control.
Nielsen J.E., Andreassen T., Gotfredsen C.H., Olsen D.A., Vestergaard K., Madsen J.S., Kristensen S.R, & Pedersen S. (2024). Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study. Metabolomics, 20(1), 12.
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