Patients in the treatment group were treated with the S-1 and oxaliplatin regimen. These patients received 30-40 mg/m 2 S-1 (Lunan Pharmaceutical, Shandong, China) by oral administration twice daily for 14 days combined with intravenous infusion of 130 mg/m 2 oxaliplatin (Jiangsu Hengrui Pharmaceuticals Co., Ltd., Jiangsu, China) for 3 hours on day 1. During the regimen, tropisetron was used as an antiemetic. Patients in the control group were treated with the XELOX regimen. These patients received 1000 mg/m 2 ×eloda (Roche Pharmaceuticals Ltd., Switzerland) by oral administration twice daily for 14 days combined with oxaliplatin in the same dosage and length of time as the treatment group. The treatment cycle was repeated every three weeks for both groups. The total treatment periods of the two groups were 4 to 6 cycles.
Oxaliplatin
Manufactured by Roche
Sourced in Switzerland, China
Oxaliplatin is a platinum-based chemotherapy drug used to treat certain types of cancer. It functions as a DNA-damaging agent, interfering with the replication and transcription of DNA in cancer cells.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using oxaliplatin
1
S-1 and Oxaliplatin Regimen vs. XELOX in Cancer
2
Metastatic Colorectal Cancer Treatment
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SOX regimen: oxaliplatin (Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, China) at 130 mg/m2 (intravenous infusion administered in 500 mL of 5% glucose over a period of 2 h) and S-1 (Taiho Pharmaceutical Co., Ltd., Tokyo, Japan) of 60 mg (orally administered twice a day on days 1–14). XELOX regimen: oxaliplatin at 130 mg/m2 (intravenous infusion administered in 500 mL of 5% glucose over a period of 2 h) and capecitabine (Shanghai Roche Pharmaceuticals Ltd., Shanghai, China) of 1,500 mg (orally administered twice a day on days 1–14). A cycle of the two regimens were repeated every 3 weeks.
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