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Linoleic acid

Manufactured by Carl Roth
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Linoleic acid is an essential fatty acid found in various oils and fats. It is a colorless, odorless, and viscous liquid. Linoleic acid is commonly used as a chemical standard and reference material in analytical applications.

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Lab products found in correlation

Chrysin, by Carl Roth (2 mentions) Hexane, by Carl Roth (2 mentions) Apigenin, by Merck Group (2 mentions) Methanol, by Avantor (2 mentions) Hplc grade acetonitrile, by Avantor (2 mentions) Abietic acid, by Merck Group (2 mentions) Chloroform d1, by Avantor (2 mentions) Barnstead micropure system, by Thermo Fisher Scientific (2 mentions) Pinocembrin 7 methyl ether, by Carl Roth (2 mentions) Formic acid, by Honeywell (2 mentions) Ethyl acetate, by Carl Roth (2 mentions) Arachidonic acid, by Merck Group (1 mentions) α linolenic acid, by Merck Group (1 mentions) Triphenylphosphine, by Merck Group (1 mentions)

3 protocols using linoleic acid

1

Extraction and Isolation of Natural Compounds

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Solvents for different steps in analyses were partially denatured ethanol (AustrAlco, Spillern, Austria) for extraction, hexane, ethyl acetate (both Carl Roth, Karlsruhe, Baden-Württemberg, Germany) and methanol (VWR, Radnor, PA, USA) for open column chromatography and TLC, chloroform-d1 (VWR) and pyridine-d5 (Armar, Döttingen, Aargau, Switzerland) for NMR.
HPLC mobile phases consisted of ultrapure water prepared from deionized water with a Barnstead MicroPure system (Thermo Fisher Scientific, Waltham, MA, USA), HPLC-grade acetonitrile (VWR) and formic acid for LC-MS (Honeywell, Charlotte, NC, USA).
Reference substances were abietic acid contributed by the Department of Pharmaceutical Chemistry, University of Graz, Austria, apigenin (Sigma-Aldrich, St. Louis, MO, USA), chrysin, pinocembrin-7-methyl ether (pinostrobin), linoleic acid (all Carl Roth) and oleic acid (Fluka, Buchs, St. Gallen, Switzerland).
Alperth F., Schneebauer A., Kunert O, & Bucar F. (2023). Phytochemical Analysis of Pinus cembra Heartwood—UHPLC-DAD-ESI-MSn with Focus on Flavonoids, Stilbenes, Bibenzyls and Improved HPLC Separation. Plants, 12(19), 3388.
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2

Extraction and Isolation of Natural Compounds

Check if the same lab product or an alternative is used in the 5 most similar protocols
Solvents for different steps in analyses were partially denatured ethanol (AustrAlco, Spillern, Austria) for extraction, hexane, ethyl acetate (both Carl Roth, Karlsruhe, Baden-Württemberg, Germany) and methanol (VWR, Radnor, PA, USA) for open column chromatography and TLC, chloroform-d1 (VWR) and pyridine-d5 (Armar, Döttingen, Aargau, Switzerland) for NMR.
HPLC mobile phases consisted of ultrapure water prepared from deionized water with a Barnstead MicroPure system (Thermo Fisher Scientific, Waltham, MA, USA), HPLC-grade acetonitrile (VWR) and formic acid for LC-MS (Honeywell, Charlotte, NC, USA).
Reference substances were abietic acid contributed by the Department of Pharmaceutical Chemistry, University of Graz, Austria, apigenin (Sigma-Aldrich, St. Louis, MO, USA), chrysin, pinocembrin-7-methyl ether (pinostrobin), linoleic acid (all Carl Roth) and oleic acid (Fluka, Buchs, St. Gallen, Switzerland).
Alperth F., Schneebauer A., Kunert O, & Bucar F. (2023). Phytochemical Analysis of Pinus cembra Heartwood—UHPLC-DAD-ESI-MSn with Focus on Flavonoids, Stilbenes, Bibenzyls and Improved HPLC Separation. Plants, 12(19), 3388.
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3

Analysis of Fatty Acid Derivatives

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All chemicals used were standard commercial products of analytical grade from the following companies: linoleic acid (Roth, Karlsruhe, Germany); α-linolenic acid (Roth); arachidonic acid (Sigma-Aldrich, Steinheim, Germany); triphenyl phosphine (Merck Schuchardt, Hohenbrunn, Germany); HPLC solvents (Mallinckrodt Baker, Deventer, Holland); 9(±)-HODE und 13(±)-HODE (Cayman Chemical, Tallinn, Estonia); Hydroperoxy HPLC Mix (Cayman Chemical).
Schiller D., Contreras C., Vogt J., Dunemann F., Defilippi B.G., Beaudry R, & Schwab W. (2015). A dual positional specific lipoxygenase functions in the generation of flavor compounds during climacteric ripening of apple. Horticulture Research, 2, 15003-.
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