Patients were imaged with a Siemens PET/CT nuclear medicine scanner (Siemens Biograph Vision 600 Edge) using 18F-FDG and 18F-NaF positron-emitting radiotracers as previously described [27 (link)] for, respectively, metabolic activity and microcalcification levels. Briefly, a non-enhanced low-dose CT scan to detect arterial calcium accumulation was performed and was followed immediately with a 30 min scan with the 18F-NaF and then another 30 min scan with 18F-FDG. The scans were taken in dynamic mode and yielded 35 sequential time frames. 18F-NaF and 18F-FDG were injected intravenously and consisted of a bolus of 112 ± 30 MBq and 160 ± 27 MBq, respectively, depending on the participant’s weight. The two injections were given at a 90 min interval to allow the activity of 18F-NaF to decrease before the 18F-FDG was injected. A 30 s blank scan was performed prior to injecting the 18F-FDG to eliminate any remaining 18F-NaF activity.
Biograph vision 600 edge
Manufactured by Siemens
Sourced in Germany
The Biograph Vision 600 Edge is a positron emission tomography (PET) scanner developed by Siemens. It is designed for high-performance whole-body imaging. The system features advanced detector technology and a compact design.
Automatically generated - may contain errors
Lab products found in correlation
4 protocols using biograph vision 600 edge
1
Multimodal PET/CT Imaging of Atherosclerosis
2
Multimodal PET/CT Imaging Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The PET/CT scanners are state‐of‐the art scanners from GE (GE Discovery 710 and GE Discovery MI, Hospital South West Jutland; GE Discovery MI, Odense University Hospital) and Siemens (Siemens Biograph mCT Flow 64 and Siemens Biograph Vision 600 Edge, Hospital Lillebaelt). All patients will have a CECT (according to local guidelines for contrast administration) as performed clinically in these patients in each department. The [18F]PSMA‐1007‐PET/CT scans will be performed 60 min post injection of the tracer, and Na[18F]F‐PET/CT 30 min post tracer injection.
3
PET/CT Imaging of [68Ga]Ga-DATA5m-LM4 Uptake
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The patient signed written informed consent before the study. He was intravenously injected with a dose of [68Ga]Ga-DATA5m-LM4 adopted to his body weight (1.8–2.2 MBq/kg). PET/CT images were acquired 1 h pi from the vertex to the proximal femora on a Biograph Vision 600 Edge PET/CT scanner (Siemens Healthineers AG; Erlangen, Germany). A low-dose CT scan from head to the proximate thigh was obtained for attenuation correction and anatomical mapping. Next, whole-body PET was performed with 2 min per bed position (5–7 bed positions depending on the height of the patient). The patient had a good renal function and showed no allergies to any of the ingredients of the radiopharmaceuticals. PET/CT images were anonymized and reviewed by two experienced nuclear medicine experts who were not blinded to patient medical history on the reconstructed images.
4
Fasting, FDG-PET/CT Imaging Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Patients were required to fast for > 6 h prior to scanning and finger-prick blood glucose measurement prior to scanning confirmed a venous blood glucose of < 120 mg/dl. 3.5 MBq/kg of [18F]-FDG was applied intravenously as per clinical routine. Scans were acquired at 60 min post injection of radiotracer (p.i.). All patients received regular whole-body PET scans (from skull base to the thighs) on a Biograph-Vision 600 Edge PET/CT digital scanner (Siemens, Erlangen, Germany). A non-contrast-enhanced CT scan was performed 1 h post tracer injection with slice thickness of 1.0 mm, pitch factor 1, bone and soft tissue reconstruction kernels and maximum of 120 kV and 90 mAs by applying CARE kV and CARE Dose. Immediately after CT scanning, a whole-body PET (skull base to thighs) was acquired in 3D (matrix: 440 × 440) with a zoom factor of 1.0. The emission data were corrected for randoms, scatter and decay. Reconstruction was conducted with TrueX (Point Spread Function, PSF) + time-of-flight (TOF) algorithm and 2 mm Gauss-filter was applied. TrueX is an iterative resolution recovery algorithm with PSF modelling included. Attenuation correction was performed using the low dose non-enhanced computed tomography data. Images were obtained in list mode. PET data were reprocessed to produce sinograms corresponding to 2 min/bed position (bp), 1 min/bp, and 30 s/bp.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!