Wortmannin
Wortmannin is a chemical compound that inhibits the activity of phosphoinositide 3-kinase (PI3K), an enzyme involved in various cellular processes. It functions as a potent and selective inhibitor of PI3K and related enzymes. Wortmannin is commonly used as a research tool in cell biology and biochemistry studies to investigate the role of PI3K signaling pathways.
Lab products found in correlation
4 protocols using wortmannin
Nanoparticle Synthesis and Characterization
Investigating SDF1α-Mediated Cell Migration
Investigating PI3Kγ Signaling Pathways
Pharmacological Inhibition of Viral Endocytosis
Variables from the questionnaire of the HBSC study analyzed in this study
Inhibitor | Target | Highest concentration |
---|---|---|
Pistop2 | CME | 5 μM (GCRV 104); 25 μM (GCRV JX01) |
CPZ | CME | 10 μM (GCRV 104; GCRV JX01) |
Nystatin | Caveola-dependent endocytosis | 15 μM (GCRV 104) |
methyl-β-cyclodextrin | Caveola-dependent endocytosis | 1 mM (GCRV 104) |
dynasore | Dynamin | 10 μM (GCRV 104) |
wortmannin | PI3K | 5 μM (GCRV 104) |
IPA-3 | Pak1 | 20 μM (GCRV 104) |
rottlerin | PKC | 10 μM (GCRV 104) |
NH4Cl | PH | 20 mM (GCRV 104) |
Amiloride | NHE | 10 μM (GCRV 104) |
Bafilomycin A1 | Vacuolar ATPas inhibition | 2 nM (GCRV 104) |
nocodazole | Microtubules | 10 μM (GCRV 104) |
Latrunculin B | Actin microfilaments | 0.5 μM (GCRV 104) |
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