Cxcl16 sirna

Manufactured by Santa Cruz Biotechnology

Sourced in China, United States

CXCL16 siRNA is a small interfering RNA (siRNA) targeting the CXCL16 gene. siRNAs are used to temporarily silence the expression of specific genes. The core function of CXCL16 siRNA is to downregulate the expression of the CXCL16 gene, which encodes a chemokine involved in various cellular processes.

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Lab products found in correlation

Lipofectamine 2000, by Thermo Fisher Scientific (2 mentions) Scramble control, by RiboBio (1 mentions) Lipofectamine rnaimax, by Thermo Fisher Scientific (1 mentions)

2 protocols using cxcl16 sirna

Silencing CXCL16 in Lung Cancer Cells

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RNA interfering (RNAi) was used to silence CXCL16. CXCL16 siRNA (sc-105252, Santa Cruz Biotechnology, Inc. Shanghai, China) was transfected into A549 and PC-9 cells with lipofectamine 2000 (Thermo) according to the specifications. Empty vector transfection was used as the negative control (NC). Transfection was carried on for 48 h, and the cells were used for the following experiments.

Liang K., Liu Y., Eer D., Liu J., Yang F, & Hu K. (2018). High CXC Chemokine Ligand 16 (CXCL16) Expression Promotes Proliferation and Metastasis of Lung Cancer via Regulating the NF-κB Pathway. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 24, 405-411.

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CXCL16 knockdown in A549 cells

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CXCL16 siRNA (Santa Cruz, USA), Scramble control and positive control (Ribobio, China) were transfected into A549 cells by using Lipofectamine RNAiMAX (Invitrogen, USA) following the manufacturer's instructions, and the transfection efficiency was detected by western blot 48 h later.

Ma Z., Ma C., Zhang Q., Bai Y., Mu K., Liu X, & Yang Q. (2021). Role of CXCL16 in BLM-induced epithelial–mesenchymal transition in human A549 cells. Respiratory Research, 22, 42.

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