Data were acquired at the Athinoula A. Martinos Imaging Center at MIT. Before the MRI, participants acclimated to the scanning environment and practiced staying still by undergoing a ‘mock scan’. Scanning was performed using a Siemens MAGNETOM Trio Tim 3 T MRI scanner with a 32-channel coil. A whole-brain, high-resolution, T1-weighted multi-echo structural scan (MPRAGE) was collected (ECS acquisition parameters: TR = 2530 ms, TE = 1.64 ms/3.5 ms/5.36 ms/7.22 ms, flip angle = 7°, voxel size = 1 mm isotropic, matrix size = 192 × 192, 176 sagittal slices, FOV = 192 mm; AS: TR = 2530 ms; TE = 1.64 ms/3.44 ms/5.24 ms/7.04 ms; flip angle = 7°; resolution = 1 mm isotropic). This sequence was optimized for participants with high motion (Tisdall et al., 2012 (link)). This sequence included the volumetric navigators (vNavs) prospective motion correction system, which tracked the subject's head motion and corrected the imaging coordinates to follow the subject's motion in real time (Tisdall et al., 2012 (link)). This method has been shown, when using a very similar scanning protocol, to significantly reduce motion-induced biases in cortical thickness measures (Tisdall et al., 2016 (link)).
Magnetom triotim 3 t
Manufactured by Siemens
Sourced in Germany
The Magnetom TrioTim 3 T is a magnetic resonance imaging (MRI) system produced by Siemens. It operates at a magnetic field strength of 3 Tesla, which allows for high-quality imaging of the human body. The system is designed to capture detailed anatomical and functional information for diagnostic purposes.
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Lab products found in correlation
E prime 2, by Psychology Software Tools (2 mentions)
Genesis signa 1.5 t, by GE Healthcare (1 mentions)
Magnetom avanto 1.5t, by Siemens (1 mentions)
Discovery 690, by GE Healthcare (1 mentions)
32 channel gradient head coil, by Siemens (1 mentions)
Magnetom aera 1.5t, by Siemens (1 mentions)
12 channel receive only head coil, by Siemens (1 mentions)
8 protocols using magnetom triotim 3 t
1
High-Resolution T1-Weighted MRI with Motion Correction
2
Presurgical Brain Imaging Evaluation
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As part of their presurgical evaluation, patients had an FDG‐PET and a T1‐weighted MRI scan (magnetization‐prepared rapid acquisition gradient echo) acquired. FDG‐PET scans were acquired on an Allegro (Phillips Medical Systems) at Austin Hospital with a voxel size of 2 × 2 × 2 mm or a Discovery 690 (GE Medical Systems) at Peter MacCallum Cancer Centre with a voxel size of 1.82 × 1.82 × 3.27 mm as described previously.17 The median timing of the FDG‐PET scans was 5 months preceding surgery (interquartile range = 3–10.25, range = 1–23 months). At Austin Hospital, MRI examinations were carried out on a Genesis Signa 1.5 T (GE Medical Systems) until 2005, and on a Magnetom Avanto 1.5 T (Siemens Medical Solutions) thereafter. Voxel sizes were .41 × .41 × 1.50 mm until 2006, .65 × .65 × 1.50 mm until 2011, and .77 × .77 × .80 mm thereafter. At Royal Melbourne Hospital, MRI examinations were carried out on a Genesis Signa 1.5 T (GE Medical Systems) until 2005 and on a Magnetom Trio Tim 3 T (Siemens Medical Solutions) thereafter. Voxel sizes varied depending on clinical requirements and scanner upgrades; all were higher resolution than 1 × 1 × 1 mm3.
Following the surgery, patients underwent a repeat MRI to assess the extent of the surgical resection. Eighty‐two patients were identified who had a full set of presurgical FDG‐PET and MRI and postsurgical MRI images.
Following the surgery, patients underwent a repeat MRI to assess the extent of the surgical resection. Eighty‐two patients were identified who had a full set of presurgical FDG‐PET and MRI and postsurgical MRI images.
3
fMRI Data Acquisition Protocol for Whole-Brain Neuroimaging
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The fMRI data were acquired on a Siemens Magnetom Trio Tim 3T scanner (Siemens, Erlangen, Germany) equipped with a 32-channel head coil. Data from four functional runs were collected using T-2*-weighted gradient echo echo-planar imaging (EPI) scans (acquisition parameters: TR = 7.0 s, TA = 3.0 s, delay = 4.0 s, TE = 30 ms, flip angle = 81°, FoV = 224 mm × 224 mm, 64 × 64 matrix, slice thickness = 3.5 mm, voxel resolution = 3.5 mm × 3.5 mm × 3.5 mm, bandwidth = 2056 Hz/Px, 40 interleaved axial slices providing whole-brain coverage, number of volumes = 224). A whole-brain high-resolution anatomical volume was acquired using a T-1weighted magnetization-prepared rapid gradient echo (MPRAGE) sequence (acquisition parameters: TR = 2100 ms, TE = 2.93 ms, TI = 1100 ms, flip angle = 12°, FoV = 224 mm × 256 mm, voxel resolution = 1 mm isotropic voxels). At the beginning of each run, three TRs with no data were discarded to allow for stabilization of longitudinal magnetization.
4
Functional MRI Protocol for Visual Stimuli
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The scanning procedure was carried out in a clinical approved Siemens Magnetom TrioTim 3 T (Siemens Medical Solutions, Erlangen, Germany) using the Siemens 12-channel receive-only head coil. Visual stimuli were presented using an LCD projector Silent Vision Model SV-6011 (Avotec, Inc.) and all the fMRI paradigm was programed in E-Prime 2.0® (Psychology Software Tools Inc.) and synchronized with the MRI scanner pulses.
For structural analysis and registration to standard space, a T1 high-resolution anatomical sequence, a 3D MPRAGE (magnetization prepared rapid gradient echo) was performed with the following scan parameters: repetition time (TR) = 2.3 s, echo time (TE) = 2.98 ms, 160 sagittal slices with no gap, Field-of-View (FoV) = 256 mm, flip angle (FA) = 9°, in-plane resolution = 1 × 1 mm2 and slice thickness = 1mm. The scanning parameters for fMRI acquisition were the following: TR = 3 s, TE = 39 ms, FA = 90°, in-plane resolution and slice thickness 3 mm, 41 ascending interleaved axial slices with no gap and FoV = 256 mm. Each run consisted of 254 volumes, and total paradigm scanning time was 25.4 min (2 runs).
For structural analysis and registration to standard space, a T1 high-resolution anatomical sequence, a 3D MPRAGE (magnetization prepared rapid gradient echo) was performed with the following scan parameters: repetition time (TR) = 2.3 s, echo time (TE) = 2.98 ms, 160 sagittal slices with no gap, Field-of-View (FoV) = 256 mm, flip angle (FA) = 9°, in-plane resolution = 1 × 1 mm2 and slice thickness = 1mm. The scanning parameters for fMRI acquisition were the following: TR = 3 s, TE = 39 ms, FA = 90°, in-plane resolution and slice thickness 3 mm, 41 ascending interleaved axial slices with no gap and FoV = 256 mm. Each run consisted of 254 volumes, and total paradigm scanning time was 25.4 min (2 runs).
5
3T MRI Whole-Brain Functional and Structural Protocols
6
MRI Analysis of Radiotherapy Effects
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MRI examinations were performed at the department of neuroradiology of our hospital on a Magnetom Aera 1.5 T or on a Magnetom TrioTim 3 T (both Siemens Healthineers AG., Erlangen, Germany).
The first MRI dataset displaying the new contrast-enhancing lesion after completion of radiotherapy and concomitant chemotherapy was analyzed.
The first MRI dataset displaying the new contrast-enhancing lesion after completion of radiotherapy and concomitant chemotherapy was analyzed.
7
Functional MRI of Brain Responses
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Within 1 week after clinical assessment, participants underwent the scanning procedure in a clinically approved Siemens Magnetom TrioTim 3 T (Siemens Medical Solutions, Erlangen, Germany) using the Siemens 12-channel receiveonly head coil. E-Prime 2.0 ® (Psychology Software Tools Inc.) was used to program the fMRI paradigm and the visual stimuli were presented using an LCD projector Silent Vision Model SV-6011 (Avotec, Inc.).
For structural analysis and registration to standard space, a T1 high-resolution anatomical sequence, a 3D MPRAGE (magnetization prepared rapid gradient echo) was performed with the following scan parameters: repetition time (TR) = 2.3 s, echo time (TE) = 2.98 ms, 160 sagittal slices with no gap, Field-of-View (FoV) = 256 mm, flip angle (FA) = 9°, inplane resolution = 1 × 1 mm 2 and slice thickness = 1 mm. The scanning parameters for fMRI acquisition were the following: TR = 3 s, TE = 39 ms, FA = 90°, in-plane resolution and slice thickness 3 mm, 41 ascending interleaved axial slices with no gap and FoV = 256 mm.
For structural analysis and registration to standard space, a T1 high-resolution anatomical sequence, a 3D MPRAGE (magnetization prepared rapid gradient echo) was performed with the following scan parameters: repetition time (TR) = 2.3 s, echo time (TE) = 2.98 ms, 160 sagittal slices with no gap, Field-of-View (FoV) = 256 mm, flip angle (FA) = 9°, inplane resolution = 1 × 1 mm 2 and slice thickness = 1 mm. The scanning parameters for fMRI acquisition were the following: TR = 3 s, TE = 39 ms, FA = 90°, in-plane resolution and slice thickness 3 mm, 41 ascending interleaved axial slices with no gap and FoV = 256 mm.
8
Diffusion Tensor Imaging Protocol
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Within 1 week of the clinical assessment, participants underwent the scanning procedure in a clinically approved Siemens Magnetom TrioTim 3 T (Siemens Medical Solutions, Erlangen, Germany) with a 32-channel head coil. For structural analysis and registration to standard space, a T1 high-resolution anatomical sequence (i.e. 3D magnetization prepared rapid gradient echo) was performed with the following scan parameters: repetition time (TR) = 2. molecules along the fiber and are usually seen as synonymous with white matter integrity. In contrast, MD indicates the existence of nonspecific barriers for free diffusion in the fiber. AD is a measure of longitudinal diffusion and seems to be a marker of axonal damage. Finally, RD is a measure of the transverse direction of diffusion and a good marker of altered myelination processes.
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