Eriodictyol

Stenoloma chusanum was collected from Fujian (23°54′N, 118°379′E), Guangdong (23°72′N,113°04′E), Guizhou (25°19′N, 107°17′E), Yunnan (25°11′N, 99°17′E), Hunan (26°22′N, 111°63′E), Zhejiang (28°66′N, 121°42′E), and Guangxi (22°64′N, 110°14′E), respectively. Leaves, roots, and stems were collected. N. benthamiana were grown under normal conditions with a light/dark photoperiod of 16-h/8-h at a temperature of 25 °C.
Naringenin, eriodictyol, phloretin, vitexin, isovitexin, orientin, and isoorientin were obtained from Chengdu Must Biotechnology (Chengdu, China). The UDP-glucose, UDP-galactose, and UDP- glucuronic acid were purchased from Sigma-Aldrich (St. Louis, USA). 2-hydroxyNaringenin and 2-hydroxyeriodictyol were synthesized by a plant CjFNS I/F2H following a published procedure [42 (link)].

LC-MS grade acetonitrile was purchased from Fisher Scientific (Beijing, China). De-ionized water was purified through a Milli-Q system (Millipore, Bedford, MA, USA). The analytical grade reagents used for extraction were obtained from Beijing Chemical Plant Co. Ltd. (Beijing, China). Gallic acid, ellagic acid, ethyl gallate, methyl-gallate, rutin, epicatechin, procyanidin B2, protocatechuic acid, quercitrin, hesperidin, eriodictyol, and caffeic acid were purchased from Chengdu Must Biotechnology Co. Ltd. (Chengdu, China). Oseltamivir acid was purchased from Medchem Express, LLC (Monmouth Junction, NJ, USA). Neuraminidase Inhibitors Screen Kit (NO. P0309) was purchased from Beyotime Institute of Biotechnology Co. Ltd. (Shanghai, China) and includes 10 mL buffer, 1 mL NA, 1 mL fluorescent substrate, and 1.2 mL Milli-Q water. Ninety six-well microplate reader (3925, Costar Company, Bethesda, MD, USA).