R-bupropion (R-bupropion D-Tartaric Acid Salt), S-bupropion (S-bupropion L-Tartaric Acid Salt) were purchased from Toronto Research Chemicals (Toronto, Ontario, Canada). Acetaminophen, and ammonium bicarbonate were purchased from Sigma Aldrich Chemical Co (St. Louis, MO, USA). Sprague Dawley rat brains were purchased from Innovative Research (Novi, MI, USA). Sprague Dawley rat plasma (K3EDTA, pooled) was purchased from BioIVT (Westbury, NY, USA). Methanol, ethyl acetate, and sodium phosphate monobasic were purchased from Fisher Scientific (Fairlawn, NJ, USA).
R bupropion
Manufactured by LGC
Sourced in Canada
R-bupropion is a chemical compound that functions as a laboratory standard or analytical reference material. It is used for research and development purposes, as well as for quality control and analytical testing in various laboratory settings.
Automatically generated - may contain errors
Lab products found in correlation
Methanol, by Thermo Fisher Scientific (2 mentions)
S bupropion, by LGC (2 mentions)
Bupropion, by LGC (1 mentions)
Optima grade acetonitrile, by Thermo Fisher Scientific (1 mentions)
Sodium hydroxide (naoh), by Merck Group (1 mentions)
Formic acid, by Merck Group (1 mentions)
Hydrochloric acid (hcl), by Merck Group (1 mentions)
Sodium phosphate monobasic, by Thermo Fisher Scientific (1 mentions)
Ethyl acetate, by Thermo Fisher Scientific (1 mentions)
Acetaminophen, by Merck Group (1 mentions)
Ammonium bicarbonate, by Merck Group (1 mentions)
2 protocols using r bupropion
1
Bupropion Stereoisomer Pharmacokinetics
2
Quantification of Bupropion Metabolites
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Bupropion, R-Bupropion, S-Bupropion, OH-Bupropion, R,R-OH-Bupropion, S,S-OH-Bupropion, threohydroBupropion, erythrohydroBupropion, Bupropion-d9, OH-Bupropion-d6, and threohydroBupropion-d9 were purchased from Toronto Research Chemicals (Toronto, Canada). 4′-OH-Bupropion, threo-4′-OH-hydroBupropion, and erythro-4′-OH-hydroBupropion were synthesized as previously described (Sager et al., 2016 ). Hydrochloric acid, formic acid, and sodium hydroxide were purchased from Sigma-Aldrich (St. Louis, MO). Optima grade acetonitrile, methanol, water, and pooled human liver microsomes (Gibco, mixed gender, n = 50) were purchased from Fisher Scientific (Waltham, MA). Pooled S9 fractions (n = 20, mixed gender) and recombinant P450 enzymes coexpressed with cytochrome P450 reductase and cytochrome b5 were purchased from BD Biosciences (San Jose, CA). CYP2B6 inhibitory monoclonal antibody (MAB-CYP2B6) was purchased from Corning (Corning, NY).
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