Indomethacin

Manufactured by Fagron

Sourced in Belgium

Indomethacin is a pharmaceutical ingredient used in the production of various laboratory products. It is a non-steroidal anti-inflammatory drug (NSAID) that can be utilized in the development of analytical and research tools.

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Lab products found in correlation

Ethyl cellulose, by Merck Group (2 mentions) Polyvinylpyrrolidone k 25, by BASF (2 mentions) Acetic acid, by Mallinckrodt (1 mentions) Eudragit rs po, by Evonik (1 mentions) Eudragit rl30d, by Evonik (1 mentions) Triethyl citrate tec, by Merck Group (1 mentions) Eudragit rl po, by Evonik (1 mentions) Triethyl citrate, by Merck Group (1 mentions)

3 protocols using indomethacin

Indomethacin Formulation with Whey Protein

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Indomethacin (IND; M_w = 381.37 g/mol; purity 99.1%) was purchased
from Fagron (Barsbüttel, Germany). Lacprodan BLG Pharma Grade
and β-lactoglobulin (BLG; purity ≥92%) were received
from Arla Food Ingredients (Viby, Denmark). Ethanol (95%) was purchased
from VWR International (Fontenay-sous-Bois, France) and acetic acid
(≥99,7%) from Mallinckrodt Baker B.V (Deventer, The Netherlands).

Kabedev A., Zhuo X., Leng D., Foderà V., Zhao M., Larsson P., Bergström C.A, & Löbmann K. (2022). Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin. Molecular Pharmaceutics, 19(11), 3922-3933.

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Indomethacin-Loaded Controlled-Release Beads

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Indomethacin was purchased from FAGRON Ltd. (Waregem, Belgium). Polyvinylpyrrolidone K 25 was a generous gift from BASF (Ludwigshafen, Germany). Sucrose spheres (diameter 710 -850 µm) were kindly donated by Hanns G. Werner GmbH (Tornesch, Germany). Ethyl cellulose (ethoxy content 48.0-49.5% w/w) powder and triethyl citrate (TEC) were purchased from Sigma-Aldrich (Zwijndrecht, The Netherlands). Eudragit RS ® PO (ERS), Eudragit RL ® PO and Eudragit RL ® 30D were purchased from Evonik Industries (Darmstadt, Germany).

Dereymaker A., Pelgrims J., Engelen F., Adriaensens P, & Van den Mooter G. (2017). Controlling the Release of Indomethacin from Glass Solutions Layered with a Rate Controlling Membrane Using Fluid-Bed Processing. Part 2: The Influence of Formulation Parameters on Drug Release. Molecular pharmaceutics, 14(4).

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Indomethacin Controlled-Release Formulation

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Indomethacin was purchased from FAGRON Ltd. (Waregem, Belgium). Polyvinylpyrrolidone K 25 was a generous gift from BASF (Ludwigshafen, Germany). Sucrose spheres (diameter 710 -850 µm) were kindly donated by Hanns G. Werner GmbH (Tornesch, Germany). Ethyl cellulose (ethoxy content 48.0 -49.5% w/w) powder and triethyl citrate were purchased from Sigma-Aldrich (Zwijndrecht, The Netherlands). Eudragit RL ® PO and 30 D were purchased from Evonik Industries (Darmstadt, Germany).

Dereymaker A., Scurr D.J., Steer E.D., Roberts C.J, & Van den Mooter G. (2017). Controlling the Release of Indomethacin from Glass Solutions Layered with a Rate Controlling Membrane Using Fluid-Bed Processing. Part 1: Surface and Cross-Sectional Chemical Analysis. Molecular pharmaceutics, 14(4).

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