Molecular weight chitosan

Manufactured by Merck Group

Sourced in United States

Molecular weight chitosan is a biopolymer derived from the exoskeletons of crustaceans. It is a versatile material used in various applications, including water treatment, biomedical devices, and pharmaceutical formulations. The molecular weight of chitosan can be tailored to meet specific requirements for different applications.

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Lab products found in correlation

4 protocols using molecular weight chitosan

Zeolite-Chitosan Composites for Glycerol Valorization

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All chemicals were commercial and used as received. Zeolites (3A, 4A and 5A) from BDH—Laboratory Reagent, sulfuric acid 96%, acetic acid glacial, low molecular weight chitosan, sodium sulphide nonahydrate ≥ 99.99%, and Teflon (poly(tetrafluoroethylene)) particle size 35 μm from Sigma-Aldrich, a mixture of industrial crude glycerin (82% glycerol, from a Portuguese company) and 5,5′-Dithiobis(2-nitrobenzoic Acid) > 98% from TCI.
The HeLa (human cervical cancer cell line) cells for the cytotoxicity studies were from the American Type Culture Collection, Manassas, VA, USA. The medium RPMI-1640 without L-glutamine from Corning Inc. Penicillin-streptomycin, L-glutamine, foetal bovine serum (FBS), trypsin (2.5%, without phenol red), were from Thermo Fisher Scientific (Manassas, VA, USA).

Batista M., Pinto M.L., Antunes F., Pires J, & Carvalho S. (2021). Chitosan Biocomposites for the Adsorption and Release of H2S. Materials, 14(21), 6701.

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Transdermal Delivery of Naltrexone

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Naltrexone HCl was purchased from Mallinckrodt Pharmaceuticals (Webster Groves, MO, USA). Trifluoroacetic acid (TFA); triethylamine (TEA); HPLC grade water; acetonitrile; and low (50–190 kDa, 75–85% deacetylated), medium (190–310 kDa, 75–85% deacetylated), and high (310–375 kDa, > 75% deacetylated) molecular weight chitosan were purchased from Sigma Aldrich (St Louis, MO, USA). HEPES balanced salts, sodium bicarbonate, acetic acid, and SnakeSkin^® dialysis membrane (10,000 Da molecular weight cutoff) were purchased from Thermo Scientific (Watham, MA, USA). Porcine ear skin was purchased from a local slaughterhouse.

Ogunjimi A.T., Fiegel J, & Brogden N.K. (2020). Design and Characterization of Spray-Dried Chitosan-Naltrexone Microspheres for Microneedle-Assisted Transdermal Delivery. Pharmaceutics, 12(6), 496.

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Hypericin-Chitosan Nanoemulsion for Antimicrobial and Wound Healing

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Hypericin, low molecular weight chitosan (stabilizer and viscosity enhancer) were purchased from Sigma Aldrich chemie Gmbh USA (St. Louis, MI, USA), eucalyptus oil (The major constituents of eucalyptus leaves essential oils are 1,8-cineol ranging from 49.07 to 83.59%, and α-pinene in the range of 1.27 to 26.35%), ethanol, Tween^® 80, Span^® 80, and distilled water were purchased from Dawaa Al-Gharbyah, KSA. All of the chemicals used were of the highest analytical grade.

Salawi A., Almoshari Y., Sultan M.H., Madkhali O.A., Bakkari M.A., Alshamrani M., Safhi A.Y., Sabei F.Y., Al Hagbani T., Ali M.S, & Alam M.S. (2023). Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John’s Wort Plant Constituents and Their Potential for the Treatment of Depression. Pharmaceuticals, 16(4), 490.

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Antimicrobial Edible Film Formulation

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Garlic oil (purity >99%), cinnamaldehyde (>95%), and α-tocopherol (>96%), Span 60, medium molecular weight chitosan (degree of deacetylation: 75-85% and viscosity: 200-800 cps), Trolox, TPTZ (2,4,6-tripyridyl-s-triazine), chloride acid, Iron trichloride, and ethanol were purchased from Sigma-Aldrich and Labsynth (São Paulo, Brazil) . Pigskin gelatin (type A, bloom 260º and molecular weight 5.2 x 10 4 Da) was supplied by GELNEX (Itá, SC, Brazil). Acetic acid, glycerol, Tween 20, DPPH (2,2-diphenyl-1-picrylhydrazyl), potassium persulfate, ABTS •+ 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid), sodium bromide, sodium hydroxide, nutrient broth, and Mueller Hinton agar were obtained from Sigma-Aldrich (Dorset, England, UK). Canola oil was purchased from a local supermarket. Deionized Millipore water (Elix  5UV, essential), tetracycline, and strains of bacteria P. aeruginosa (ATCC 15692) and L. monocytogenes (ATCC 35152) were provided by the microbiology laboratory at the School of Biochemical Engineering of the University of Birmingham.

Pérez-Córdoba L.J., Norton I.T., Batchelor H.K., Gkatzionis K., Spyropoulos F, & Sobral P.J.A. (2018). Physico-chemical, antimicrobial and antioxidant properties of gelatin-chitosan based films loaded with nanoemulsions encapsulating active compounds. Food Hydrocolloids., 79.

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