Log In Sign up
The largest database of trusted experimental protocols

Entinostat

Manufactured by Santa Cruz Biotechnology
Visit Supplier
Sourced in United States

Entinostat is a small-molecule inhibitor of class I histone deacetylases (HDACs). It functions by suppressing the activity of these enzymes, which play a role in regulating gene expression.

Automatically generated - may contain errors

Lab products found in correlation

4 6 diamidino 2 phenylindole dihydrochloride dapi, by Merck Group (2 mentions) As101, by Santa Cruz Biotechnology (1 mentions) Neurotensin, by Merck Group (1 mentions) Trichostatin a tsa, by Merck Group (1 mentions) Mc1568, by Selleck Chemicals (1 mentions) Sodium butyrate, by Merck Group (1 mentions) Tubacin, by MedChemExpress (1 mentions) Tazemetostat, by MedChemExpress (1 mentions) Pd98059, by Santa Cruz Biotechnology (1 mentions) Romidepsin, by MedChemExpress (1 mentions) Pci 34051, by MedChemExpress (1 mentions) Tcs jnk 6o, by Bio-Techne (1 mentions) Birb0796, by Axon Medchem (1 mentions) Vorinostat, by MedChemExpress (1 mentions)

3 protocols using entinostat

1

HDAC Inhibitor and IL-10 Synthesis Modulator Protocols

Check if the same lab product or an alternative is used in the 5 most similar protocols
Agent MS275, a selective class 1 HDAC inhibitor [13 (link)] (Entinostat, Santa Cruz Biotechnology, sc-279455), was reconstituted to a stock concentration of 10 mM in DMSO. The immunomodulator AS101 (Santa Cruz Biotechnology, sc-203825) that inhibits IL-10 protein synthesis [14 (link)] was reconstituted at a concentration of 5 mM in DMSO.
Stanfield B.A., Purves T., Palmer S., Sullenger B., Welty-Wolf K., Haines K., Agarwal S, & Kasotakis G. (2021). IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages. PLoS ONE, 16(1), e0245169.
+ Open protocol
+ Expand
2

Probing Neurotrophic Factor Signaling

Check if the same lab product or an alternative is used in the 5 most similar protocols
Cleavage-resistant mutated form of proNGF (K103A and R104A) was obtained from Alomone Labs (Jerusalem, Israel). Entinostat was obtained from Santa Cruz Biotechnology (Dallas, TX, USA). MC1568 was from SelleckChem (Houston, TX, USA). Romidepsin, PCI-34051, tubacin, 3-deazaneplanocin A hydrochloride (DZNep), and tazemetostat (TZM) were from MedChem Express Europe (Sollentuna, Sweden). VPA, trichostatin A (TSA), sodium butyrate, neurotensin, and 4’,6-diamidino-2phenylindole dihydrochloride (DAPI) were from Sigma-Aldrich (St. Louis, MO, USA).
Dedoni S., Marras L., Olianas M.C., Ingianni A, & Onali P. (2020). Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis. Apoptosis, 25(9), 697-714.
+ Open protocol
+ Expand
3

Evaluation of Pharmacological Inhibitors

Check if the same lab product or an alternative is used in the 5 most similar protocols
Recombinant human NT-3 was obtained from ImmunoTools (Friesoythe, Germany). Entinostat and PD 98,059 were obtained from Santa Cruz Biotechnology (Dallas, TX, USA). Vorinostat, romidepsin, PCI-34051, tubacin, 3-deazaneplanocin A hydrochloride, (+)-JQ-1 and tazemetostat were obtained from MedChem Express Europe (Sollentuna, Sweden). VPA and 4′,6-diamidino-2phenylindole dihydrochloride (DAPI) were obtained from Sigma-Aldrich (St. Louis, MO, USA). BIRB 0796 was obtained from Axon Medchem BV (Groningen, The Netherlands), whereas TCS JNK6o was from Tocris Bioscience (Bristol, UK).
Dedoni S., Marras L., Olianas M.C., Ingianni A, & Onali P. (2021). The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic Acid. International Journal of Molecular Sciences, 22(15), 7790.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!