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3.0 t system

Manufactured by Siemens
Sourced in Germany

The 3.0-T system is a magnetic resonance imaging (MRI) device produced by Siemens. It generates a 3.0 Tesla (T) static magnetic field, which is used to acquire high-quality images of the human body for medical diagnosis and research purposes. The core function of the 3.0-T system is to provide a powerful and stable magnetic field to enable detailed anatomical and functional imaging.

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6 protocols using 3.0 t system

1

Detailed Lower Limb MRI Protocol

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On a follow-up visit at 8 years old, the patient (II-1) was evaluated using a 3.0-T system (Siemens AG, Munich, Germany). Lower limb imaging was obtained in the axial [field of view (FOV), 24–32 cm; slice thickness, 6 mm; and slice gap, 0.5–1.0 mm] and coronal planes (FOV, 38–40 cm; slice thickness, 4–5 mm; slice gap, 0.5–1.0 mm). The following protocol was used: T1-weighted spin-echo (SE) [repetition time (TR)/echo time (TE) 570-650/14-20, 512 matrices], T2-weighted SE (TR/TE 2800-4000/96-99, 512 matrices), and fat-suppressed T2-weighted SE (TR/TE 3090-4900/85-99, 512 matrices).
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2

Intervertebral Disc Degeneration in Rabbits

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After 1 and 2 weeks following initial annulus puncture, 20 rabbits were randomly selected for X-ray and MRI assessments. Lumbar computed radiography (CR) imaging was performed by a Small Animal Digital X-ray Imaging System (SEDECAL, Spain), and MRI tests were performed via a 3.0 T system (Siemens, German).
The radiographic results were analyzed by a PACS system (Neusoft, China) by two independent radiologists. We obtained the value of the disc height index (DHI) according to Lu [28 (link)]. The change in DHI was expressed as DHI %. Referring to the modified Thompson classification [29 (link)], the T2-weighted MRI images were classified as grade I to grade IV [27 (link)].
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3

Multimodal Imaging Techniques for Comprehensive Evaluation

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CEUS: The ultrasound equipment was as follows: Convex transducers and a Contrast Harmonic Imaging mode were used. A 2.4-mL bolus of SonoVue (Bracco Imaging SpA, Milan, Italy) was injected into the antecubital vein and then received a flush with 5 mL of 0.9% saline solution. The examination needs to be continued for up to 6 min.
CECT: CECT was performed with one of the following equipment: a 64-detector row (Aquilion CXL, Toshiba Medical System, Tokyo, Japan) or 320-detector row CT machine (Aquilion One, Toshiba Medical System, Tokyo, Japan). 1.5 mL/kg of contrast media (Ultravist, Bayer, Germany) was injected into an antecubital vein at a rate of 3.0 mL/s via a pump injector (P3T abdomen module, Medrad Inc.).
CEMRI: MRI examination was performed by using a 3.0-T system (Siemens Healthineers). Gd-EOB-DTPA (Primovist®, 0.1 mL/kg body weight) with a flow rate of 1 mL/s was injected into an antecubital vein.
Imaging protocols and scanning parameters of CEUS, CECT, and CEMRI examination are described in Supplementary Material S1.
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4

Assessment of IVD Height Changes

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One, two and four weeks after the AF acupuncture procedure, 9 rabbits were randomly selected for X-ray and MRI examination. Lumbar computed radiography imaging was performed by Digital X-ray Imaging System (Siemens, Berlin, German), and MRI tests were performed via a 3.0 T system (Siemens, Berlin, German). The changes in IVD height were evaluated by the disc height index (DHI) which was expressed as the mean of the 3 measurements from midline to the boundary of the central 50% of disc width divided by the mean of the 2 adjacent vertebral body heights. Changes in the DHI of punctured discs were expressed as a percentage (%DHI = post-punctured DHI/pre-punctured DHI × 100). All results were analyzed independently by two radiologists and the mean values used.
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5

Aortic Pulse Wave Velocity Measurement

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Participants underwent cardiovascular MRI using a 3.0-T system (Siemens, Erlangen, Germany). The aPWV was assessed as follows: Phase-contrast cine imaging was applied to assess aPWV between the ascending aorta and descending aorta at the level of the right pulmonary artery with slice orientation perpendicular to the aorta (Fig. 1).27 (link) The following sequence parameters were used: field of view, 270 × 270 mm; voxel size, 1.64 × 1.4×7 mm; repetition time/echo time, 8.8/2.7 ms; velocity encoding, 200 cm/s, retrospective ECG gating, and 80 acquired phases. The aPWV was determined from the time delay of the aortic flow-versus-time curves at locations in the ascending aorta and proximal descending aorta, using a cross-correlation method on the systolic upstroke part of the flow curves.28 (link) The aPWV was calculated as Δx/Δt, where Δx is the aortic path length along a midline in the vessel lumen, and Δt is the transit time (Fig. 1).27 (link) Myocardial fibrosis was quantified by measuring extracellular volume (ECV) on cardiovascular MRI, as previously described.25
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6

ALPPS Protocol for Liver Volume Measurement

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About 1 week after the stage-1 ALPPS, CT, or MRI was performed to measure liver volumes. CT data were analyzed and reconstructed using medical image analysis software (Myrian XP Liver; Intrasense; France). MRI data were analyzed and reconstructed using a 3.0-T system (Siemens Healthineers) with an 8-channel phased-array coil and scanning. The standard liver volume (SLV) was calculated by the Urata formula (31 (link)). When the FLR/SLV ratio reached >40%, performing the stage-2 ALPPS was considered to be safe for patients with cirrhosis, whereas a ratio >30% was sufficient for patients with no evidence of cirrhosis. The correlation between the FLR volume at the baseline (V0) and after the stage-1 ALPPS (V1) was calculated by the formula: %FLR volume increase = (V1 – V0)/V0 ×100 to evaluate the FLR volume increment (32 (link)). The kinetic growth rate (KGR), which reflects the daily increase in the volume of the FLR, was also calculated.
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