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Anti ps15p53 ab1431 and anti polq ab80906

Manufactured by Abcam
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Anti-pS15p53 (ab1431) is a rabbit monoclonal antibody that recognizes the phosphorylated serine 15 residue of the p53 protein. Anti-POLQ (ab80906) is a rabbit polyclonal antibody that detects the POLQ (polymerase theta) protein.

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Lab products found in correlation

Histone h3 fl 136 and anti vinculin h 10, by Santa Cruz Biotechnology (2 mentions) Anti ps824kap 1 a300 767a, by Fortis Life Sciences (2 mentions) Anti ps317γh2ax 05636, by Merck Group (2 mentions) Anti brdu 555627, by BD (2 mentions) Parpi rucaparib ag 014699, by Selleck Chemicals (2 mentions) Abt 888, by Abbvie (2 mentions) Mitomycin c mmc, by Merck Group (2 mentions) Hydroxyurea hu, by Merck Group (2 mentions) Anti flag m2, by Merck Group (2 mentions)

Close spelling variants of this product

Ab1431 (29 citations)

2 protocols using anti ps15p53 ab1431 and anti polq ab80906

1

Antibody-based DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies used in this study included: anti-PCNA (PC-10), anti-FANCD2 (FI-17), anti-RAD51 (H-92), anti-GST (B14), and Histone H3 (FL-136) and anti-vinculin (H-10) (Santa Cruz); anti-Flag (M2) (Sigma); anti-pS317CHK1 (2344), anti-pT68CHK2 (2661) (Cell signalling); anti-pS824KAP-1 (A300-767A) (Bethyl); anti-pS317γH2AX (05636) (Millipore); anti-pS15p53 (ab1431) and anti-POLQ (ab80906) (abcam); anti-BrdU (555627) (BD Pharmingen). Mitomycin C (MMC), cis-diamminedichloroplatinum(II) (Cisplatin, CDDP), and Hydroxyurea (HU) were purchased from Sigma. The PARPi rucaparib (AG-014699) was purchased from Selleckchem and ABT-888 from AbbVie. Rucaparib was used for all in vitro assays and ABT-888 was used for all in vivo experiments.
Ceccaldi R., Liu J.C., Amunugama R., Hajdu I., Primack B., Petalcorin M.I., O'Connor K.W., Konstantinopoulos P.A., Elledge S.J., Boulton S.J., Yusufzai T, & D'Andrea A.D. (2015). Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair. Nature, 518(7538), 258-262.
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2

Antibody-based DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies used in this study included: anti-PCNA (PC-10), anti-FANCD2 (FI-17), anti-RAD51 (H-92), anti-GST (B14), and Histone H3 (FL-136) and anti-vinculin (H-10) (Santa Cruz); anti-Flag (M2) (Sigma); anti-pS317CHK1 (2344), anti-pT68CHK2 (2661) (Cell signalling); anti-pS824KAP-1 (A300-767A) (Bethyl); anti-pS317γH2AX (05636) (Millipore); anti-pS15p53 (ab1431) and anti-POLQ (ab80906) (abcam); anti-BrdU (555627) (BD Pharmingen). Mitomycin C (MMC), cis-diamminedichloroplatinum(II) (Cisplatin, CDDP), and Hydroxyurea (HU) were purchased from Sigma. The PARPi rucaparib (AG-014699) was purchased from Selleckchem and ABT-888 from AbbVie. Rucaparib was used for all in vitro assays and ABT-888 was used for all in vivo experiments.
Ceccaldi R., Liu J.C., Amunugama R., Hajdu I., Primack B., Petalcorin M.I., O'Connor K.W., Konstantinopoulos P.A., Elledge S.J., Boulton S.J., Yusufzai T, & D'Andrea A.D. (2015). Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair. Nature, 518(7538), 258-262.
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