Discovery rx 64 slice pet ct

Manufactured by GE Healthcare

Sourced in United States

The Discovery RX 64-slice PET/CT is a diagnostic imaging system designed to capture high-quality images of the human body. It combines positron emission tomography (PET) and computed tomography (CT) technologies to provide detailed information about the structure and function of various organs and tissues.

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Lab products found in correlation

Biograph mct 128 slice pet ct, by Siemens (2 mentions)

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Discovery RX (36 citations) Discovery 64-slice CT (2 citations)

2 protocols using discovery rx 64 slice pet ct

Prostate Cancer PET/CT Imaging Protocol

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As per our standard practice, patients were asked to be nil per os (with the exception of water and medications) for at least 4 h prior to radiotracer injection. ¹⁸F-DCFPyL was synthesized as previously described [13 (link)]. Integrated PET/CT using either a Discovery RX 64-slice PET/CT (General Electric, Waukesha, WI, USA) or a Biograph mCT 128-slice PET/CT (Siemens, Erlangen, Germany) operating in 3D emission mode with CT attenuation correction was performed in all patients. ¹⁸F-DCFPyL ≤9 mCi (≤333 MBq) was administered intravenously and after an uptake time of approximately 60 min, acquisitions from the mid-thigh to the vertex of the skull were conducted, covering six to eight bed positions (depending on patient height and the scanner) with patients in the supine position.

Werner R.A., Sheikhbahaei S., Jones K.M., Javadi M.S., Solnes L.B., Ross A.E., Allaf M.E., Pienta K.J., Lapa C., Buck A.K., Higuchi T., Pomper M.G., Gorin M.A, & Rowe S.P. (2017). Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia. Annals of Nuclear Medicine, 31(9), 696-702.

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Preparation and Imaging Protocol for [18F]DCFPyL PET/CT

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As per standard practice at our institution, patients were asked to be nil per os (with the exception of water and medications) for a minimum of 4 h prior to radiotracer injection. [¹⁸F]DCFPyL was synthesized under current good manufacturing practice conditions as has been previously described [16 (link)]. Integrated PET/CT using either a Discovery RX 64-slice PET/CT (General Electric, Waukesha, Wisconsin, USA) or a Biograph mCT 128-slice PET/CT (Siemens, Erlangen, Germany) was performed in all patients. The PET scanners were operated in 3D emission mode with CT attenuation correction. [¹⁸F]DCFPyL ≤333 MBq (≤9 mCi) was administered through a peripheral intravenous catheter and after an uptake time of approximately 60 min, acquisitions from the mid-thigh to the vertex of the skull were conducted, covering six to eight bed positions. The patients were in the supine position. For further details, please refer to [17 (link)].

Werner R.A., Bundschuh R.A., Bundschuh L., Lapa C., Yin Y., Javadi M.S., Buck A.K., Higuchi T., Pienta K.J., Pomper M.G., Lodge M.A., Gorin M.A, & Rowe S.P. (2020). Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake. Molecular imaging and biology, 22(1), 190-197.

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