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Cetostearyl alcohol

Manufactured by Merck Group
Sourced in Germany

Cetostearyl alcohol is a white, waxy solid that is commonly used as a pharmaceutical excipient. It is a mixture of stearyl alcohol and cetyl alcohol, which are long-chain fatty alcohols derived from natural sources. Cetostearyl alcohol is typically used in the formulation of various personal care and pharmaceutical products, where it serves as an emulsifying agent, thickening agent, and lubricant.

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4 protocols using cetostearyl alcohol

1

Detailed Protocol for Lipid-Based Formulations

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ITZ, cetyl alcohol, and cetostearyl alcohol were purchased from Sigma-Aldrich Company (St. Louis, MO, USA). Labrafac® CC (caprylic/capric triglyceride) and glyceryl monostearate were obtained from Gattefosse (Lyon, France). Tween® 80 (polyoxyethylene sorbitan monooleate), Tween® 40 (polyoxyethylene sorbitan monopalmitate), Span® 60 (sorbitan monostearate), Span® 80 (sorbitan monooleate), stearic acid, paraffin oil, mineral oil, and propylene glycol were purchased from Duksan Pure Chemicals Co., Ltd. (Seoul, Korea). Polyglyceryl-3 methylglucose distearate was procured from Goldschmidt (Essen, Germany). Acetonitrile and methanol of high-performance liquid chromatography (HPLC) grade were purchased from J.T. Baker Chemical Company (Phillipsburg, NJ, USA). Distilled and deionized water was used to prepare all the solutions.
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2

Antimicrobial Formulations: Diverse Ingredients

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The chemicals, media, and solvents used in this study were anhydrous sodium sulfate, cetostearyl alcohol, hard paraffin, liquid paraffin, propylene glycol, stearyl alcohol, and wool fat and were purchased from Sigma-Aldrich (Germany). Polyethylene glycol (PEG) 4000 and PEG 600 were obtained from BDH (England). Sodium lauryl sulfate was purchased from LABORT Fine Chemicals (India) and white petrolatum USP was purchased from EPHARM (Ethiopia). Muller-Hinton agar, Muller-Hinton broth, nutrient agar, nutrient broth, Sabouraud dextrose agar, Sabouraud dextrose broth, tryptone soya, agar and tryptone soya broth were purchased from Oxoid (UK). Yeast extract was purchased from LABORT (India).
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3

Solid Lipid Nanoparticles from Pterodon Essential Oil

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Sucupira essential oil was obtained from the fruits of genus Pterodon plant and used as liquid lipid. Imwitor® 900 K (glycerol monostearate, type II) with a monoglyceride content of 40–55% (m/m) and Dynasan® 116 (tripalmitin) were purchased from Cremer Oleo GmbH & Co. KG company (Hamburg, Germany) and used as solid lipid. Kollivax® GMS II (glycerol monostearate) was purchased from BASF (Ludwigshafen am Rhein, Germany) and used as solid lipid. Compritol® 888 ATO (glyceryl dibehenate) was purchased from Gattefossé (Lyon, France). Cetostearyl alcohol was purchased from Sigma-Aldrich (Madrid, Spain) and used as solid lipid.
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4

Lipid-Based Formulation Development and Characterization

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Loteprednol etabonate (LE) was gratefully donated by Deva İlaç Sanayi ve Tic. A.Ş. (Turkey). Compritol® 888 ATO, Compritol® E ATO, and 1-tetradecanol were kindly provided by Gattefossé (France). Cutina® CP, Geleol™, Gelucire® 50/13, Imwitor® 491, Imwitor® 900K, Isopropyl myristate, and cetostearyl alcohol were purchased from Ataman Kimya A.Ş. (Turkey). Oleic acid and castor oil were purchased from BASF (Germany). Olive oil purchased from Arpaş Arifoğlu Pazarlama Dağıtım ve Ticaret A.Ş. (Turkey). Cremephor® EL, cetostearyl alcohol (CA), Nacol 16-98, and Cremephor® RH40 were provided from Sigma-Aldrich (Germany). Lutrol® F68, Tween® 80, and Labrasol® were purchased from BASF (USA). All other chemicals were of analytical grade.
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