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Signa 1.5 t scanner

Manufactured by GE Healthcare
Sourced in United States

The Signa 1.5 T scanner is a magnetic resonance imaging (MRI) system manufactured by GE Healthcare. It operates at a magnetic field strength of 1.5 Tesla, which is a common field strength used in clinical MRI applications. The Signa 1.5 T scanner is designed to acquire high-quality MRI images for diagnostic purposes.

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18 protocols using signa 1.5 t scanner

1

Probabilistic Tractography of Brain Connectivity

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Each individual's MRI data were collected during a single session on a GE Signa 1.5 T scanner. Processing of diffusion imaging data included corrections for imaging errors, after which semi-automated AutoPtx35 (link) pipeline, which consists of FMRIB Software Library (FSL, https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FSL) tools, was used to run probabilistic tractography in participant native space to extract brainstem, projection, association, callosal, thalamic, and limbic system fibers, resulting in 27 WM tracts in each individual. Further details of image acquisition and processing are provided in Supplementary Methods.
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2

Structural MRI and MEG Connectivity Parcellation

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Structural magnetic resonance (MR) scans (voxel size 1 mm × 1 mm × 1 mm) were performed on a General Electric Signa 1.5 T scanner. The T1 images were processed using the default FreeSurfer (v. 6.0.0) ‘recon-all’ pipeline. For the MEG analysis, the cortical surface was parcellated into 448 similar-size labels, as described by Khan et al. [40 (link)].
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3

MRI Imaging Protocol for Whole-Brain Functional and Structural Analysis

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MRI scans were performed using a GE Signa 1.5 T scanner (General Electric, Waukesha, WI) equipped with standard head coils. An adjustable mirror located above the participant's eyes was used to view the back-projected images on a screen placed at the foot of the scanner bed. In each functional imaging session, 217 volumes (28 contiguous axial 4.4 mm thick slices) covering the whole brain were acquired using a T2*-sensitive spiral sequence (TR=2300 ms; TE=40 ms; flip angle 85°; matrix 64×64; FOV 200×200 mm). The first three volumes were discarded to allow for T1 equilibrium effects, and the data from the remaining 214 volumes were used in the analysis.
T1-weighted IR-Prepped 3D FSPGR anatomical images (120 contiguous axial 1.1 mm thick slices) were acquired (TR=12 ms; TE=5.4 ms; flip angle 20°; matrix 256×256; FOV 200×200 mm) to assess brain structure.
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4

High-Resolution T1-Weighted Brain Imaging

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High-resolution T1-weighted images were collected on a GE Signa 1.5 T scanner (Milwaukee, WI) using a high-resolution volumetric spoiled-grass axial series with repetition time = 35 ms, echo time = 5 ms, matrix size = 256 × 256, field of view = 24 cm, number of excitation = 1, and voxel dimensions of 0.94 × 0.94 × 1.5 mm. All images were being processed by FreeSurfer, version 5.1.0 (http://surfer.nmr.mgh.harvard.edu), an image analysis tool that uses a surface-based method to perform cortical reconstruction and volumetric segmentation. The technical details of this tool have been described elsewhere [32] (link), [33] (link), [34] (link), [35] (link), [36] (link) (Supplementary Material)
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5

Resting-State fMRI and Structural MRI Protocol

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MRI scans were acquired with a GE Signa 1.5 T scanner (General Electric, Waukesha, WI) equipped with standard head coils. A 5 minute (299 s) resting-state echo-planar imaging (EPI) scan (36 axial slices; slice thickness = 4.4 mm; TR = 2300 ms; TE = 40 ms; matrix 64 × 64; FOV 20 cm; 130 volumes) was acquired for each participant. Participants were instructed to rest quietly with their eyes open and to remain awake during the scan. High resolution IR-Prepped 3D FSPGR T1-weighted anatomical images (120 contiguous axial 1.1 mm thick slices) were also acquired (TR = 12 ms; TE = 5.4 ms; flip angle 20°; matrix 256 × 256; FOV 20 cm).
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6

Multimodal Neuroimaging of Concussion

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MRI was performed on a General Electric (GE) Signa 1.5 T scanner
(n = 16 concussion with 109 total scans,
n = 32 controls with 235 total scans) or a 3T Philips
Achieva (n = 42 concussion with 100 total scans,
n = 79 controls with 171 total scans). GE 1.5-T scans
used a high-resolution volumetric spoiled gradient recalled acquisition in a
steady state series (axial acquisition, repetition time = 35msec, echo time
= 5msec, flip angle = 45°, field of view = 24 cm, matrix = 256
× 256, number of excitations = 1, voxel dimensions = 0.94 ×
0.94 × 1.5 mm slice thickness). T1-weighted magnetization-prepared
rapid gradient echo (MPRAGE) scans were acquired on a 3T Philips Achieva
(repetition time [TR] = 6.8msec, echo time [TE] = 3.2msec, flip angle =
8°, image matrix = 256 256, 170slices, pixel size = 1 × 1 mm,
slice thickness = 1.2 mm).
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7

Vocal Tract Dynamics in Spontaneous and Read Speech

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Five female native speakers of American English were engaged in a simple dialog with the experimenter on topics of a general nature (e.g., “what music do you listen to …”, “tell me more about your favorite cuisine …,” etc.) to elicit spontaneous spoken responses while inside the MR scanner. For each speech “turn,” audio responses and MRI videos of vocal tract articulation were recorded for 30 seconds and time-synchronized with the audio. The same speakers were also recorded/imaged while reading TIMIT shibboleth sentences and the rainbow passage during a separate scan. The spontaneous and read speech data represent the two speaking styles considered in this study. Details regarding the recording and imaging setup can be found in [13] (link) and [16] (link). Midsagittal real-time MR images of the vocal tract were acquired with a repetition time of TR = 6.5 ms on a GE Signa 1.5 T scanner with a 13 interleaf spiral gradient echo pulse sequence. The slice thickness was approximately 3 mm. A sliding window reconstruction at a rate of 22.4 frames per second was employed. Field-of-view (FOV), which can be thought of as a zoom factor, was set depending on the subject's head size. Further details, and sample MRI movies can be found at http://sail.usc.edu/span.
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8

Structural MRI Brain Reconstruction

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Structural MR scans (voxel size 1 x 1 x 1 mm) were performed on a General Electric Signa 1.5 T scanner. The obtained T1 images were processed using default FreeSurfer (v.6.0.0) ‘recon-all’ reconstruction algorithm [62 (link)]. The results of this reconstruction were used to create the source model as described below.
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9

Automated MRI Volumetric Analysis Protocol

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All MRI data were obtained at Chulalongkorn Hospital on a GE Signa 1.5T scanner with the latest software and hardware versions that included an isotropic 3D MRI acquisition (3D spoiled gradient echo, sagittal plane with full brain coverage, minimum echo time with full echo, TR=20ms, flip angle=50 with resolution 1×1×1.4 mm3). Images were processed using Freesurfer 5.0 (Fischl, et al., 2004). Freesurfer processing included extraction of non-brain tissue, normalization of voxel intensity as a result of MR bias, transformation of each brain to Talairach space, and segmentation of subcortical white matter and deep gray matter volumetric structures using voxel identity probabilities. Proper segmentation was reviewed and manually edited using built in freesurfer data quality modification tools (tmkedit) to ensure accurate classification of structures.
ROIs chosen for statistical analyses included: total gray matter, subcortical gray matter, total white matter, caudate, putamen, and thalamus. Volumes for each ROI were normalized to adjust for differences in head size (Free et al, 1995 (link)).
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10

Multimodal Neuroimaging of Concussion

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MRI was performed on a General Electric (GE) Signa 1.5 T scanner
(n = 16 concussion with 109 total scans,
n = 32 controls with 235 total scans) or a 3T Philips
Achieva (n = 42 concussion with 100 total scans,
n = 79 controls with 171 total scans). GE 1.5-T scans
used a high-resolution volumetric spoiled gradient recalled acquisition in a
steady state series (axial acquisition, repetition time = 35msec, echo time
= 5msec, flip angle = 45°, field of view = 24 cm, matrix = 256
× 256, number of excitations = 1, voxel dimensions = 0.94 ×
0.94 × 1.5 mm slice thickness). T1-weighted magnetization-prepared
rapid gradient echo (MPRAGE) scans were acquired on a 3T Philips Achieva
(repetition time [TR] = 6.8msec, echo time [TE] = 3.2msec, flip angle =
8°, image matrix = 256 256, 170slices, pixel size = 1 × 1 mm,
slice thickness = 1.2 mm).
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