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Cobra c2

Manufactured by Cordis
Sourced in United States

The Cobra C2 is a lab equipment product designed for precise fluid handling and mixing. It features a dual syringe pump system that can accurately dispense and aspirate liquids. The Cobra C2 is capable of handling a wide range of sample volumes and viscosities, making it a versatile tool for various laboratory applications.

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4 protocols using cobra c2

1

Robotic Angiography for DEB-TACE Procedure

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All interventions were performed in the same robotic angiography suite (Artis Zeego Q, Siemens Healthcare, Forchheim, Germany). The arterial system was accessed by puncture of the right common femoral artery, after introduction of a 4 F sheath (Terumo, Leuven, Belgium) over a 0.035 in. guidewire (Terumo, Leuven, Belgium). In cases of unclear origin of the hepatic arteries a straight diagnostic catheter was introduced and aortography was performed. The celiac trunk was accessed with a cobra (C2) or sidewinder (SIM1) configurated catheter (Cordis, Fremont, California, U.S.) and celiacography was performed. After selective catheterization of the common hepatic artery, overview angiography was performed for assessment of the number and extent of tumor blushes and tumor feeding vessels. A 2.7 F microcatheter (Progreat, Terumo) was introduced for super selective catheterization of the tumor feeders. Epirubicin loaded microparticles (100–300 μm, DC-Beads, BTG, Langweid/Augsburg, Germany) were cautiously applied under fluoroscopy control until near stasis was reached, according to the guidelines of DEB-TACE [4 (link)]. Finally, completion angiography from the common hepatic artery was performed.
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2

Uterine Artery Embolization Procedure

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The interventions were performed in a dedicated angiography suite. After applying local anesthesia, unilateral percutaneous femoral artery access was gained. In selected cases, the pre-installed epidural or general anesthesia was maintained throughout the embolizations. 4 F catheters (Cobra C2, Cordis Corp., Miami Lakes, FL, USA) were advanced into both uterine arteries or at least into the anterior divisions of the respective internal iliac arteries. In some cases, at the discretion of the interventional radiologist, coaxial microcatheters (Progreat®, 2.7 F, Terumo Corp., Leuven, Belgium, China) were utilized to engage the uterine arteries. Depending on the chosen catheter, embolizations were performed either with gelfoam pledgets or gelfoam slurry, which are considered temporary embolic agents, until flow stasis in the uterine arteries was achieved (Fig. 1).
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3

Uterine Artery Embolization Procedure

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The interventions were performed in a dedicated angiography suite. After applying local anesthesia, unilateral percutaneous femoral artery access was gained. In selected cases, the pre-installed epidural or general anesthesia was maintained throughout the embolizations. 4 F catheters (Cobra C2, Cordis Corp., Miami Lakes, FL, USA) were advanced into both uterine arteries or at least into the anterior divisions of the respective internal iliac arteries. In some cases, at the discretion of the interventional radiologist, coaxial microcatheters (Progreat®, 2.7 F, Terumo Corp., Leuven, Belgium, China) were utilized to engage the uterine arteries. Depending on the chosen catheter, embolizations were performed either with gelfoam pledgets or gelfoam slurry, which are considered temporary embolic agents, until flow stasis in the uterine arteries was achieved (Fig. 1).
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4

Transarterial Embolization for Gastrointestinal Bleeding

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An 18-gauge single-wall needle was used to perform a retrograde puncture of the common femoral artery. Using the Seldinger technique, a 5-F vascular sheath was placed over a 0.035-inch guidewire. Depending on the bleeding site identified on CTA images, selective catheterization of the celiac axis, superior mesenteric and/or inferior mesenteric arteries was performed using 5 Fr catheters (Cobra C2 or Simmon-1; Cordis, Miami Lakes, FL, USA). Angiography was performed to confirm the bleeding and to localize the source (active contrast extravasation, contrast blushing), a pseudoaneurysm or an abnormal vessel (truncated, irregular wall). Subsequently, whenever possible, a superselective catheterization using a microcatheter (1.7-2.1Fr Echelon, Medtronic, USA; 2Fr Stridesmooth+, Asahi Intecc co., Japan; 2.7Fr Progreat, Terumo, Japan) was coaxially advanced into the target artery.
TAE was performed using different coils depending on the operator's preference: 0.018 inch microcoils, such as Nester or Tornado (Cook Medical, Bloomington, USA, n = 25), Gelfoam (Pfizer, n = 6) or a combination of both (n = 9), or n-butyl cyanoacrylate mixed with iodized oil (Histoacryl/Lipiodol, n = 1).
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