The resting-state functional magnetic resonance imaging (rsfMRI) data were acquired on a 3T Siemens Trio TIM MR scanner equipped with a 12-channel phased array receiver-only head coil at the Imaging Center for Brain Research, Beijing Normal University. The rsfMRI data were obtained using a gradient-echo EPI sequence with the following two parameter sets: (A) TR = 2000 ms, TE = 30 ms, 33 transverse slices, slice thickness = 3.5 mm, gap = 0.7 mm, flip angle = 90°, FOV = 224 mm × 224 mm, matrix = 64 × 64, and 240 volumes covering the whole brain; (B) TR = 3000 ms, 40 transverse slices, slice thickness = 3.5 mm, no gap, 160 volumes, and the other parameters were identical to those of (A). For each parameter set, all participants were scanned under EC and EO conditions in turn. A total of 4 types of rsfMRI scans (i.e., AO, AC, BO, and BC) were obtained for each participant in the same session. In order to reduce the sequence effect, the order of data acquisition was counterbalanced across all participants. In addition, a high-resolution 3D brain structural image was also acquired for each participant using the MP-RAGE sequence with the implementation of the parallel imaging scheme GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA; Griswold et al., 2002 (link)) and an acceleration factor of 2.
Tim trio mr scanner
Manufactured by Siemens
Sourced in Germany
The Tim Trio MR scanner is a magnetic resonance imaging (MRI) device designed and manufactured by Siemens. It is a medical imaging system that uses strong magnetic fields and radio waves to create detailed images of the body's internal structures. The core function of the Tim Trio MR scanner is to provide high-quality diagnostic imaging capabilities for healthcare professionals.
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Lab products found in correlation
12 channel head coil, by Siemens (11 mentions)
32 channel head coil, by Siemens (2 mentions)
Mpms xl 7 system, by Quantum Design (1 mentions)
Cary 100, by Agilent Technologies (1 mentions)
Vertex 70, by Bruker (1 mentions)
32 channel phase array head coil, by Siemens (1 mentions)
Mprage, by Siemens (1 mentions)
Ingenia scanner, by Philips (1 mentions)
Standard 12 channel head coil, by Siemens (1 mentions)
34 protocols using tim trio mr scanner
1
Resting-State fMRI Acquisition and Preprocessing
2
Resting-state fMRI Acquisition Protocol
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All MRI data were acquired on a 3T Siemens Trio TIM MR scanner powered with a total imaging matrix (TIM) technique at the Imaging Center for Brain Research, Beijing Normal University. The resting-state functional magnetic resonance imaging (rsfMRI) data were acquired using a 12-channel phased array receiver-only head coil. The rsfMRI data were obtained using a gradient-echo EPI sequence with the following two parameter sets: (A) TR = 2000 ms, TE = 30 ms, 33 transverse slices, slice thickness = 3.5 mm, gap = 0.7 mm, flip angle = 90°, FOV = 224 mm × 224 mm, matrix = 64 × 64, and 240 volumes covering the whole brain; (B) TR = 3000 ms, 40 transverse slices, slice thickness = 3.5 mm, no gap, 160 volumes, and the other parameters identical to those of (A). For each parameter set, all subjects underwent the rsfMRI scan under both conditions (EC and EO) in turn. Thus, there were four types of rsfMRI scan: AO, AC, BO, and BC. For each subject, all four scans were performed in the same session. The order of data acquisition was counterbalanced across all subjects. In addition, we also acquired high-resolution 3D brain structural images for each subject by using MP-RAGE sequence with the implementation of parallel imaging scheme GRAPPA (GeneRalized Autocalibrating Partially Parallel Acquisitions) (Griswold et al., 2002 (link)) and the acceleration factor 2.
3
Resting-State fMRI in Healthy Subjects
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All participants were scanned using a 3T Siemens Trio Tim MR scanner at the Brain Imaging Center at SCNU, Guangdong, China. The r-fMRI data were collected using a GE-EPI sequence: 32 axial slices, repetition time (TR) = 2 s, echo time (TE) = 30 ms, slice thickness = 3.5 mm, no gap, flip angle (FA) = 90°, matrix = 64 × 64, and field of view (FOV) = 192 mm × 192 mm. The subjects were instructed to lie down with their eyes closed, and to remain quiet during the scans while thinking of nothing in particular.
After scanning, a total of 240 volumes were obtained from each participant.
After scanning, a total of 240 volumes were obtained from each participant.
4
Characterization of Magnetite Nanoparticles
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TEM, HR-TEM images and the SAED pattern of nanocubes were obtained using a high resolution transmission electron microscope (TEM -Tecnai G2 F30) operating at 300 kV. UV-Vis absorption spectra were recorded using a UV-Vis spectrophotometer (Varian -Cary 100). FT-IR spectra was recorded by using an FT-IR spectrometer (Bruker-Vertex 70). Magnetic measurements (M-H and M-T curves) were recorded on a Quantum Design MPMS-XL-7 system. MR phantom experiments were performed at room temperature on a 3 T Siemens TrioTim MR scanner. Various concentrations (3 to 60 µM) of magnetite nanoparticles were prepared for MRI phantom study. T 1 -Weighted and T 2 -weighted phantom MR images of magnetite nanoparticles were acquired using a spin echo (SE) sequence under the following parameters: TR/TE = 1000/12 ms (T 1 ), TR/TE = 10 000/330 ms (T 2 ), (slice thickness = 3 mm, flip angle = 90°, acquisition matrix = 384 pixels × 384 pixels, FoV = 120 × 120 mm 2 ).
5
Brain Imaging with 3T MRI Protocols
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Participants were scanned at National Magnetic Resonance Research Center (UMRAM) in Bilkent University by using a 3T Siemens TimTrio MR scanner with a 32-channel phase array head coil. In order to minimize head movement, relevant foam paddings were put under their skull, around their neck, and under their legs. Stimuli were presented on an MR-compatible LCD screen (TELEMED, 60 Hz refresh rate, 800 × 600 pixel, 32 inches) and seen through a mirror system mounted on top of the head coil that is 168 cm away.
A high-resolution T1-weighted anatomical image covering the entire brain was acquired before the functional scans using the following acquisition parameters: TE = 2.92 ms, TR = 2.6 s, flip angle = 12°, Acceleration factor = 2, 176 sagittal slices with 1 mm × 1 mm × 1 mm resolution). Later on, for each of the eight experimental runs, functional images were acquired using echo-planar imaging (EPI) sequence (TR = 3 s, TE = 30 ms, flip angle = 90°, 96 × 96 matrix with FOV 240, 49 horizontal slices with 2.5 mm slice thickness). Each run started with the collection of 5 dummy scans to ensure that MR signal reached a steady state.
A high-resolution T1-weighted anatomical image covering the entire brain was acquired before the functional scans using the following acquisition parameters: TE = 2.92 ms, TR = 2.6 s, flip angle = 12°, Acceleration factor = 2, 176 sagittal slices with 1 mm × 1 mm × 1 mm resolution). Later on, for each of the eight experimental runs, functional images were acquired using echo-planar imaging (EPI) sequence (TR = 3 s, TE = 30 ms, flip angle = 90°, 96 × 96 matrix with FOV 240, 49 horizontal slices with 2.5 mm slice thickness). Each run started with the collection of 5 dummy scans to ensure that MR signal reached a steady state.
6
Multimodal Neuroimaging in Friedreich's Ataxia
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A subgroup of 15 FRDA patients and 15 pairwise‐matched controls (Table 1 ) received structural and functional MRI on a 3 Tesla Tim Trio MR scanner (Siemens Medical Systems, Erlangen, Germany). For the fMRI scan, T2*‐weighted images parallel to the AC/PC‐line were obtained using an echo‐planar imaging sequence (EPI) with the following parameters: TR = 4000 msec, TE = 30 msec, FoV = 200 mm, 64 × 64 matrix, 36 slices and slice thickness = 3.12 mm. Images were acquired within the first 2080 msec of the TR, leaving 1920 msec of no data acquisition, in which the subject could generate words.26 High‐resolution T1‐weighted images were acquired using a magnetization‐prepared rapid gradient‐echo sequence (TR = 2300 msec, TE = 2.98 msec, TI = 900 msec, FoV = 250 mm, 240 × 256 matrix, 176 sagittal slices, slice thickness = 1 mm). DTI was performed using a spin‐echo echo‐planar sequence (TR = 8800 msec TE = 84 msec, FoV = 224 mm, 112 × 112 matrix, 2 mm slice thickness) including seven b0‐images without diffusion gradients and 48 with diffusion weightings along predefined gradient directions with b = 1000 sec/mm2.
7
Multimodal Neuroimaging Protocol for Anxiety
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A 3-tesla scanner (Siemens Tim Trio MR scanner) is utilised for the neuroimaging component of the study. Structural MRI: A high-resolution (1×1×1 mm) T1 weighted scan will be performed. MRS: To measure the level of metabolite concentrations within the region of interest (anterior cingulate cortex (ACC)), single voxel MRS will be applied. PRESS sequence (TE = 30, TR = 2000, Ave = 128, weak water suppression) is first conducted to measure the main metabolism, followed by MEGA-PRESS (TE = 68, TR = 2000, suppression frequency = 1.95 ppm, Ave = 64) [54 (link), 56 –58 (link)] sequence at the identical location to measure concentration of GABA. Finally a water-unsuppressed sequence (16 averages) will be conducted for quantification. Functional MRI: Resting state fMRI (EPI sequence, TE/TR = 30/2500, 3×3×3 mm, 33 slices, 10-min scan acquisitions) will be conducted with the subject’s eyes closed in addition to task-based cognitive activation fMRI study utilising IAPS to elicit anxiety (EPI sequence, TR = 2000, 3×3×3 mm, 27 mins).
8
High-resolution Multimodal Brain Imaging
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A 3 Tesla TIM Trio MR scanner (Siemens, Erlangen, Germany) was used to perform MRI using a 32-channel phased-array radiofrequency head coil. High-resolution MRI of each subject’s brain was collected using an axial 3D magnetization prepared rapid-acquisition gradient-echo (MPRAGE) T1-weighted sequence (echo time [TE] = 1.64 ms, repetition time [TR] = 2530 ms, TI = 1200 ms, flip angle of 7°) with a 256-mm field of view (FOV), and 160 1.0-mm contiguous partitions at a 256 × 256 matrix. Whole-brain diffusion weighted images were collected at b = 1000 s/mm2 with 30 directions using 2-mm voxel resolution in-plane and through-plane.
9
High-resolution Multimodal Brain Imaging
10
High-Resolution Brain Imaging with MRI
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A 3 Tesla TIM Trio MR scanner (Siemens, Erlangen, Germany) was used to perform MRI using a 32‐channel phased‐array radiofrequency head coil. High‐resolution MRI of each subject's brain was collected using an axial 3D magnetization prepared rapid‐acquisition gradient‐echo (MPRAGE) T1‐weighted sequence (echo time [TE] = 1.64 ms, repetition time [TR] = 2,530 ms, TI = 1,200 ms, flip angle of 7°) with a 256‐mm field of view (FOV), and 160 1.0‐mm contiguous partitions at a 256 × 256 matrix. Whole‐brain diffusion weighted images were collected at b = 1000 with 30 directions using 2‐mm voxel resolution in‐plane and through‐plane.
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