Artemisinin

Manufactured by Yuanye Bio-Technology

Sourced in China

Artemisinin is a key active compound extracted from the Artemisia annua plant. It is a natural compound with anti-malarial properties. The core function of Artemisinin is to serve as a pharmaceutical ingredient for the production of anti-malarial drugs.

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Lab products found in correlation

4 protocols using artemisinin

Artemisinin's Cytotoxic Effect Analysis

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Artemisinin was purchased from Shanghai Yuanye Biological Technology Co., Ltd. (63968649). RPMI1640 and fetal bovine serum were purchased from Gibco. Propidium iodide (PI) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were purchase from Sigma. Oligo-dT primers and rTaq premix were purchased from Takara, Otsu, Japan. Reverse transcriptase (M-MLV), RNase inhibitor, Taq polymerase and nuclease-free water were all purchased from Promega, Madison, WI, USA. Anti-bcl-2 (0032R, Bioss), anti-bax (0127R, Bioss), anti-caspase-3 (0081R, Bioss), and anti-β-actin (RG00120, Solarbio life sciences) polyclonal or monoclonal antibodies were purchased from Bioss and Solarbio life sciences. HRP-labeled goat anti-rabbit/mouse IgG was purchased from ZSGB-BIO (Beijing, China). All the plates used in present study were purchased from Nunc. All chemicals used were of analytical grade.

Chen J., Zhang L, & Hao M. (2018). Effect of artemisinin on proliferation and apoptosis-related protein expression in vivo and in vitro. Saudi Journal of Biological Sciences, 25(7), 1488-1493.

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Investigating Anti-Inflammatory Effects of TCM Formulation

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Dexamethasone was obtained from Beijing Solarbia Technology Co., Ltd. (Beijing, China). IL-6, IL-1β, TNF-α enzyme-linked immunosorbent assay (ELISA) and arginase-1 (Arg-1) ELISA kit was obtained from Shanghai Enzymatic Union Biotechnology Co., Ltd. (Shanghai, China). Inducible nitric oxide synthase (iNOS) and bicinchoninic acid (BCA) protein concentration assay kits were purchased from Nanjing Jiancheng Biological Engineering Institute (Nanjing, China). CD86 polyclonal antibody and CD206 polyclonal antibody were purchased from Proteintech Group, Inc. (Wuhang, China). Poly(I:C) and reference standards of chlorogenic acid, forsythoside A, liquiritin, saikosaponin A, baicalin, arginine, magnolol, protocatechuic acid, 4-hydroxyacetophenone, aristolochic acid A and artemisinin were obtained from Shanghai Yuanye Biotechnology Co., Ltd. (Shanghai, China). All herbs used to prepare QWJR were obtained from Sinopharm Yunnan, Ltd. (Kunming, China).

Li Q., Zhang T., Wang Y., Yang S., Luo J., Fang F., Liao J., Wen W., Cui H, & Shang H. (2022). Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism. Frontiers in Pharmacology, 13, 891851.

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Evaluation of Purified Phytochemicals

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Ferulic acid (98% purity), liquiritin (98% purity), magnolol (98% purity), and ginsenoside Rb2 (93.8% purity) were obtained from the National Institutes for Food and Drug Control (NIFDC, Beijing, China). Borneol (98% purity), ginsenoside Rc (98% purity), artemisinin (99% purity), chenodeoxycholic acid (98% purity), daidzin (98% purity), and bacopaside I (98% purity) were purchased from Shanghai yuanye Bio-Technology Co., Ltd. Other reagents were of analytical purity.

Li P., Chen C., Zhang W., Yu D., Liu S., Zhao J, & Liu A. (2019). Detection of Vasodilators From Herbal Components by a Transcriptome-Based Functional Gene Module Reference Approach. Frontiers in Pharmacology, 10, 1144.

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Quantitative Analysis of Terpenes

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D(+)-Camphor (98% purity, CAS No: 464-49-3) used as internal standard, perilla ketone (CAS No: 553-84-4), dihydroartemisinic acid (CAS No: 85031-59-0) and artemisinin (CAS No: 63968-64-9) standards were purchased from Shanghai Yuanye Biotechnology Co. LTD (Shanghai, China). The isoegoma ketone (CAS No: 34348-59-9) and raspberry ketone (CAS No: 5471-51-2) standard was purchased from Chengdu DeSiTe Biological Technology Co., Ltd (Chengdu, China). β-Caryophyllene (CAS No: 87-44-5) was purchased from Beijing Solarbio Science & Technology Co.,Ltd (Beijing, China). (+)-Pulegone (CAS No: 89-82-7) and (-)-menthone (CAS No: 14073-97-3) standards were purchased from Sigma-Aldrich (Shanghai, China). (+)-Isomenthone (CAS No: 1196-31-2), 3-nonen-2-one (CAS No: 14309-57-0), 2-nonanone (CAS No: 821-55-6) standards were purchased from Shanghai Macklin Biochemical Technology Co., Ltd (Shanghai, China). Artemisinic acid (CAS No: 80286-58-4) was purchased from Chengdu Biochem Pure Biotechnology Co., LTD (Chengdu, China). 4-hydroxybenzalacetone (CAS No: 22214-30-8) standard was purchased from Nantong Feiyu Biotechnology Co., LTD (Nantong, China).

Zhou P., Shao Y., Jiang Z., Dang J., Qu C, & Wu Q. (2023). The revealing of a novel double bond reductase related to perilla ketone biosynthesis in Perilla frutescens. BMC Plant Biology, 23, 345.

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