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Anti brdu 555627

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Anti-BrdU (555627) is a laboratory reagent used to detect and quantify DNA synthesis in cells. It is a primary antibody that specifically binds to bromodeoxyuridine (BrdU), a thymidine analog incorporated into newly synthesized DNA during the S-phase of the cell cycle.

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Lab products found in correlation

Histone h3 fl 136 and anti vinculin h 10, by Santa Cruz Biotechnology (2 mentions) Anti ps824kap 1 a300 767a, by Fortis Life Sciences (2 mentions) Anti ps317γh2ax 05636, by Merck Group (2 mentions) Anti ps15p53 ab1431 and anti polq ab80906, by Abcam (2 mentions) Parpi rucaparib ag 014699, by Selleck Chemicals (2 mentions) Abt 888, by Abbvie (2 mentions) Mitomycin c mmc, by Merck Group (2 mentions) Hydroxyurea hu, by Merck Group (2 mentions) Anti flag m2, by Merck Group (2 mentions)

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Anti-BrdU (92 citations)

2 protocols using anti brdu 555627

1

Antibody-based DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies used in this study included: anti-PCNA (PC-10), anti-FANCD2 (FI-17), anti-RAD51 (H-92), anti-GST (B14), and Histone H3 (FL-136) and anti-vinculin (H-10) (Santa Cruz); anti-Flag (M2) (Sigma); anti-pS317CHK1 (2344), anti-pT68CHK2 (2661) (Cell signalling); anti-pS824KAP-1 (A300-767A) (Bethyl); anti-pS317γH2AX (05636) (Millipore); anti-pS15p53 (ab1431) and anti-POLQ (ab80906) (abcam); anti-BrdU (555627) (BD Pharmingen). Mitomycin C (MMC), cis-diamminedichloroplatinum(II) (Cisplatin, CDDP), and Hydroxyurea (HU) were purchased from Sigma. The PARPi rucaparib (AG-014699) was purchased from Selleckchem and ABT-888 from AbbVie. Rucaparib was used for all in vitro assays and ABT-888 was used for all in vivo experiments.
Ceccaldi R., Liu J.C., Amunugama R., Hajdu I., Primack B., Petalcorin M.I., O'Connor K.W., Konstantinopoulos P.A., Elledge S.J., Boulton S.J., Yusufzai T, & D'Andrea A.D. (2015). Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair. Nature, 518(7538), 258-262.
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2

Antibody-based DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies used in this study included: anti-PCNA (PC-10), anti-FANCD2 (FI-17), anti-RAD51 (H-92), anti-GST (B14), and Histone H3 (FL-136) and anti-vinculin (H-10) (Santa Cruz); anti-Flag (M2) (Sigma); anti-pS317CHK1 (2344), anti-pT68CHK2 (2661) (Cell signalling); anti-pS824KAP-1 (A300-767A) (Bethyl); anti-pS317γH2AX (05636) (Millipore); anti-pS15p53 (ab1431) and anti-POLQ (ab80906) (abcam); anti-BrdU (555627) (BD Pharmingen). Mitomycin C (MMC), cis-diamminedichloroplatinum(II) (Cisplatin, CDDP), and Hydroxyurea (HU) were purchased from Sigma. The PARPi rucaparib (AG-014699) was purchased from Selleckchem and ABT-888 from AbbVie. Rucaparib was used for all in vitro assays and ABT-888 was used for all in vivo experiments.
Ceccaldi R., Liu J.C., Amunugama R., Hajdu I., Primack B., Petalcorin M.I., O'Connor K.W., Konstantinopoulos P.A., Elledge S.J., Boulton S.J., Yusufzai T, & D'Andrea A.D. (2015). Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair. Nature, 518(7538), 258-262.
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