Ingenia 3.0 t mri

All subjects underwent image acquisition with Philips Ingenia 3.0 T MRI. The subjects were in a supine position, their head was fixed with a foam pad, earplugs were worn to reduce noise, and eyes were closed, breathed evenly, and kept in a relaxed state. A 32-channel phased array head coil is used. All subjects underwent routine MRI scans of the head to exclude organic lesions in the brain. (1) ASL: FOV 24 cm × 24 cm, slice thickness 4 mm, TR 4000 ms, TE 15 ms, acquisition times 3, and postmarking delay time 1500 ms. (2) MRS: the posterior cingulate gyrus, frontal white matter, and other brain regions are located by three planes; the posterior cingulate gyrus is located above the parieto-occipital sulcus and posterior to the corpus callosum, with a voxel size of 20 mm × 20 mm × 20 mm; the frontal white matter is located at the center of the semioval, and the voxel size is 10 mm × 10 mm × 10 mm. Single pixel point-resolved spectroscopy (PRESS),TR = 2000 ms,TE = 35 ms,FOV = 22 × 22 cm, matrix1024 × 1024,NSA = 128,flip = 90°; automatic shimming, water suppression.

Both the patient and control groups underwent the same MRI protocol using the 8-channel head orthogonal coil of Philips INGENIA 3.0T MRI (Philips Co., Holland) in Third Xiangya Hospital, Central South University. The patient group was examined within 3 days after mTBI injuries (the same day as the neuropsychological examination). All subjects were placed on the scanning bed with their heads fixed while keeping their heads as still as possible, staying awake, and not thinking anything or processing any tasks during the examination. The specific scanning parameters were the same as those in our previous mTBI studies, as shown in the supplementary materials [1 (link)].