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2 protocols using indirubin

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Pharmacological Modulators of Signaling Pathways

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AhR ligands: 2,3,7,8‐tetrachlorodibenzo‐p‐dioxine (TCDD; Sigma Aldrich, St Louis, MO, USA, 48599), 2‐(1' H‐indole‐3′‐carbonyl)‐thiazole‐4‐carboxylic acid methyl ester (ITE; Medchem Express, Monmouth Junction, NJ, USA HY‐19317), benzo‐a‐pyrene (BaP; Sigma Aldrich, B1760), indirubin (Selleckchem, Houston, TX, USA, S2386), FICZ (6‐formylindolo [3,2‐b]carbazole; Medchem Express, HY‐12451), and CH‐223191 (Selleckchem, S7711).

BRAF inhibitors: vemurafenib (Vem, PLX4032; Selleckchem, S1267), dabrafenib (Dab, GSK2118436; Selleckchem, S2807), and encorafenib (LGX818; Selleckchem, S7108).

SRC inhibitors: dasatinib (Selleckchem S1021) and bosutinib (SKI‐606; Selleckchem, S1014).

EGFR inhibitors: gefitinib (Selleckchem S1025) and erlotinib (Selleckchem S7786).

Hsp90 inhibitor: NVP‐HSP990 (Selleckchem S7097).

DMSO – Sigma‐Aldrich (D8418).

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2

Dietary Compounds from Selleckchem in Research

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The following dietary compounds were purchased from Selleckchem: apigenin (Selleckchem, Cat#- S2262), baicalein (Selleckchem, Cat#- S2269), baicalin (Selleckchem, Cat#- S2268), berberine hydrochloride (Selleckchem, Cat#- S2271), Cat#- S2268), caffeic acid (Selleckchem, Cat#- S2277), dihydromyricetin (Selleckchem, Cat#- S2399), emodin (Selleckchem, Cat#- S2295), (−)-epigallacatechin gallate (Selleckchem, Cat#- 2250), gossypol acetate (Selleckchem, Cat#- S2303), hematoxylin (Selleckchem, Cat#- S2384), indirubin (Selleckchem, Cat#- S2386), kaempferol (Selleckchem, Cat#- S2314), luteolin (Selleckchem, Cat#- S2320), morin hydrate (Selleckchem, Cat#- S2325), myricetin (Selleckchem, Cat#- S2326), myricitrin (Selleckchem, Cat#- S2327), palmatine chloride (Selleckchem, Cat#- S2397) and quercetin dihydrate (Selleckchem, Cat#- S2347).
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