Copd 6

Manufactured by Vitalograph

Sourced in Ireland, United Kingdom

The COPD-6 is a portable handheld spirometer designed for the screening and monitoring of Chronic Obstructive Pulmonary Disease (COPD). It measures six key lung function parameters, including FEV1, FVC, and FEV1/FVC ratio.

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Lab products found in correlation

Quadscan 4000, by Bodystat (1 mentions) Nellcor, by Medtronic (1 mentions)

7 protocols using copd 6

Longitudinal Lung Function Evaluation

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Lung function was measured using the portable spirometer COPD-6 (Vitalograph Ltd., County Clare, Ireland). The FEV1 and forced expiratory volume in 6 s (FEV6) of each participant were measured three times at intervals of several minutes. The reading with the maximum sum of FEV1 and FEV6 was chosen as the final result. The percentage of the predicted value was calculated. About 3 years later, participants were called for a second lung function test so that the FEV1 decline rate could be assessed.

Hu Z.W., Zhao Y.N., Cheng Y., Guo C.Y., Wang X., Li N., Liu J.Q., Kang H., Xia G.G., Hu P., Zhang P.J., Ma J., Liu Y., Zhang C., Su L, & Wang G.F. (2016). Living near a Major Road in Beijing: Association with Lower Lung Function, Airway Acidification, and Chronic Cough. Chinese Medical Journal, 129(18), 2184-2190.

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Pulmonary Function Assessment via COPD-6

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Pulmonary function was assessed based on FEV1 measured using the diagnostic pneumatometer COPD-6 (Vitalograph Ltd., Ennis, Ireland, 2016), and the measurement error was ±2%. The measurement was taken following the COPD practice guidelines (2012), wherein the patient bites on a disposable mouthpiece in a resting state and breathes in and out to the extent possible. Three measurements were taken, and the highest value was used, wherein a higher value indicated better pulmonary function.

Jang K.S., Oh J.E, & Jeon G.S. (2022). Effects of Simulated Laughter Therapy Using a Breathing Exercise: A Study on Hospitalized Pulmonary Tuberculosis Patients. International Journal of Environmental Research and Public Health, 19(16), 10191.

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Microspirometry for Lung Function Assessment

Cited 1 time

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Microspirometry will be performed with minimal coaching by a trained researcher using a simple handheld microspirometer (Vitalograph COPD6), to measure forced expiratory volume (FEV)₁, FEV₆ and FEV₁/FEV₆ ratio. Each participant will perform three blows using the device, after which the researcher will record the highest FEV₁ and FEV₆ values, and the FEV₁/FEV₆ ratio. For the main analysis, FEV₁/FEV₆ ratios of <0.7528 (link) and <0.7829 (link) will be assessed to indicate a positive test.

Pan Z., Dickens A.P., Chi C., Kong X., Enocson A., Adab P., Cheng K.K., Sitch A.J., Jowett S, & Jordan R. (2020). Study to evaluate the effectiveness and cost-effectiveness of different screening strategies for identifying undiagnosed COPD among residents (≥40 years) in four cities in China: protocol for a multicentre cross-sectional study on behalf of the Breathe Well group. BMJ Open, 10(11), e035738.

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Postoperative Pain Management After RAMIE

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The primary endpoint was postoperative pain assessed by NRS (0–10) at POD1, POD3 and POD7 after RAMIE. Secondary outcome parameters were use of additional analgesia or side effects of the analgesic therapies (hypotension, paresthesia, nausea or vomiting), differences in forced expiratory volume in 1 s (FEV1) at POD1, POD3 and POD7 corrected for preoperative FEV1 (flows measured with COPD 6, Vitalograph Inc., United Kingdom), duration of intensive care and hospital stay. Postoperative complications were graded according to the modified Clavien Dindo scale (MCDC) or Esophagectomy Complications Consensus Group (ECCG) definitions [28 (link),29 (link)].

Rosner A.K., van der Sluis P.C., Meyer L., Wittenmeier E., Engelhard K., Grimminger P.P, & Griemert E.V. (2023). Pain management after robot-assisted minimally invasive esophagectomy. Heliyon, 9(3), e13842.

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Diagnostic Criteria for COPD Progression

Cited 1 time

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FEV1 and FEV6 were measured using the portable spirometer COPD 6 (Vitalograph Ltd., County Clare, Ireland), as previously reported (10 (link)). When the FEV1/FEV6 ratio was <0.7, a bronchodilator test was performed. COPD was diagnosed when the FEV1/FEV6 was <0.7 after the bronchodilator test (11 (link)).
Changes in prebroncholilator FEV1 were based on the slope defined by the first and last data points. Annualized FEV1 was classified into three categories based on an extreme definition of rapid decline (annualized absolute loss of FEV1 >40, 20–40, and <20 mL/y), as previously reported (12 (link)).

Liao J.P., Wang X., Liu F., Cheng Y., Hu Z.W., Zhang L.N., Xia G.G., Zhang C., Ma J, & Wang G.F. (2021). Serum surfactant protein D, lung function decline, and incident chronic obstructive pulmonary disease: a longitudinal study in Beijing. Journal of Thoracic Disease, 13(1), 92-100.

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Anthropometric and Physiological Measures

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Stature was measured to the nearest 0.1 cm (Holtain stadiometer, Crymych, UK) and body mass to the nearest 0.1 kg (Seca, Birmingham, UK), with body-mass index (BMI) subsequently calculated. Body-fat percentage (and subsequent fat-free mass) was identified using bioelectrical impedance (Quadscan 4000; Bodystat, Douglas, Isle of Man). Estimates of arterial blood oxygenation (SaO2) were recorded using a pulse-oximeter (Nellcor; Medtronic, Minneapolis, USA). Measures of forced expiratory volume in one-second (FEV1), forced vital capacity (FVC) were obtained using a spirometer (Vitalograph Alpha; Vitalograph, Buckingham, UK and COPD-6, Vitalograph, Buckingham, UK) and normalised to percentage of their predicted value ( 16).

Tomlinson O.W., Shelley J., Trott J., Bowhay B., Chauhan R, & Sheldon C.D. (2020). The feasibility of online video calling to engage patients with cystic fibrosis in exercise training. Journal of telemedicine and telecare, 26(6).

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Mastery-based COPD-6 and Breathe-easy App

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Participants allocated to MASTERY were provided with a COPD-6 ® (Vitalograph Ltd, Ennis, Ireland) to measure their lung function (FEV 1 and FEV 6 ) daily and a specifically designed Breathe-easy © application installed on a loaned "smart" mobile phone to record asthma symptoms and asthma medication usage weekly. Participants were also prompted to follow an individualised WAAP specifically developed by the study team as part of the intervention package. An automated feedback message regarding her asthma status was sent weekly based on the Breathe-easy © algorithm that was based on National Asthma Council 3 and Global Initiative for Asthma (GINA) guidelines. 5 All data were transmitted automatically to a central server to which the researchers, participants and their health professionals had secure access. Participants' health professionals were contacted by one of the researchers, a trained asthma educator (EZ), if any medication changes or unscheduled asthma-related visits were needed.

Zairina E., Abramson M.J., McDonald C.F., Li J., Dharmasiri T., Stewart K., Walker S.P., Paul E, & George J. (2016). Telehealth to improve asthma control in pregnancy: A randomized controlled trial. Respirology (Carlton, Vic.), 21(5).

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