Glycidyl methacrylate

Laminarin
(LAM) from Eisenia bicyclis (CAS: 9008–22–4)
and lithium phenyl(2,4,6-trimethylbenzoyl)phosphinate
(LAP) were purchased from Biosynth. Tetraethyl orthosilicate (TEOS,
98%), hexadecyltrimethylammonium bromide (CTAB, 98%), calcium
chloride anhydrous, dry dimethyl sulfoxide (DMSO, p.a. ≤ 0.02%
water), and formaldehyde were acquired from Sigma-Aldrich. 3-(Trimethoxysilyl)propyl
acrylate (stabilized with BHT) (TMOS-PA, 93%) and glycidyl methacrylate
(stabilized with MEHQ, 95%) were purchased from TCI Chemicals. Disodium
hydrogen phosphate monohydrate and alginic acid sodium salt (M_w 10,000–600 000 Da, Alginate)
were bought from PanReac AppliChem. 4-Dimethylaminopyridine (DMAP,
99%) and toluene (extra dry, 99.85%) were obtained from ACROS Organics.
Unless otherwise specified, all chemicals were used as received without
further purification.

All chemicals were used as received unless otherwise specified. Styrene and glycidyl methacrylate (GMA) were purchased from TCI Chemicals and Sigma-Aldrich, respectively. Azobisisobutyronitrile (AIBN) was purchased from the Junsei Chemical Co., Ltd., and recrystallized from methanol prior to use. Tetrahydrofuran (THF), toluene, methyl ethyl ketone (MEK), and methanol were purchased from Honeywell Chemicals, Samchun Chemicals, Alfa Aesar, and Daejung Chemicals, respectively. 3-Mercaptopropionic acid (MPA), lithium hydroxide (LiOH), polystyrene (PS, M_n = 35 kg/mol), and poly(glycidyl methacrylate) (PGMA, M_n = 10–20 kg/mol) were purchased from Sigma-Aldrich.

GC (catalog no. HY-135969; ≥80% deacetylation, ≥400 degree of polymerization, molecular weight = ~82 kDa) was obtained from MedChemExpress (NJ, USA). Glycidyl methacrylate was supplied by Tokyo Chemical Industry Co. Ltd. (Chuo-ku, Tokyo, Japan). Ammonium persulfate (catalog no. 7727-54-0), N,N,N′,N′-tetramethyl ethylenediamine (TEMED; catalog no. 110-18-9), lipopolysaccharide (LPS; catalog no. L2880), and DNA, sodium salt extracted from salmon testes (catalog no. D1626) were acquired from Sigma-Aldrich (Seoul, South Korea). DOX (hydrochloride salt, >99%) was purchased from LC Laboratories (MA, USA). Cyanine7 N-hydroxysuccinimide ester was provided by Lumiprobe (MD, USA). Recombinant mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) was sourced from BioLegend (CA, USA). The D-Plus CCK cell viability assay kit was procured from Dongin Biotech Co. (Seoul, Korea). LDS 751 (catalog no. L7595), RPMI 1640 medium (catalog no. 22400, Gibco), fetal bovine serum (FBS; catalog no. 16000044, Gibco), and penicillin/streptomycin (catalog no. 15140163, Gibco) were obtained from Thermo Fisher Scientific (MA, USA).