Sulfasalazine

Manufactured by Santa Cruz Biotechnology

Sulfasalazine is a laboratory product manufactured by Santa Cruz Biotechnology. It functions as a chemical compound used for research purposes.

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Lab products found in correlation

Sc 47778, by Santa Cruz Biotechnology (1 mentions) Ab62352, by Abcam (1 mentions) Mab3249, by R&D Systems (1 mentions) Diclofenac sodium salt, by Merck Group (1 mentions) Taurocholic acid sodium salt hydrate, by Merck Group (1 mentions) Sodium glycocholate hydrate, by Merck Group (1 mentions) Allura red ac, by Merck Group (1 mentions) Cromolyn sodium salt, by Merck Group (1 mentions) Salicylic acid, by Merck Group (1 mentions) Tartrazine, by Merck Group (1 mentions) Hemin, by Frontier Scientific (1 mentions)

Spelling variants of this product

Sulfasalazine (SSZ) (2 citations)

2 protocols using sulfasalazine

Oxidative Stress Pathway Evaluation

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Sulfasalazine and BSO were from Santa Cruz Biotechnology, DYC was from Tokyo Chemical Industry and OXY was from Alfa Chemistry. For immunoblot analysis, human xCT was detected with rabbit monoclonal antibodies (#12691, 1:1000 dilution; Cell Signaling Technology), Nrf2 with rabbit monoclonal antibodies (ab62352, 1:500 dilution; Abcam) and β‐actin with mouse monoclonal antibodies (sc‐47778, 1:500; Santa Cruz Biotechnology). For immunocytofluorescence analysis, 4‐HNE was detected with mouse monoclonal antibodies (MAB3249, 1:100; R&D Systems). For immunohistochemical or immunohistofluorescence analysis, 4‐HNE was detected with mouse monoclonal antibodies (HNEJ‐2, 1:100; JaICA) and cyclooxygenase‐2 (COX‐2) was detected with rabbit polyclonal antibodies (HPA001335, 1:100; Atlas Antibodies).

Otsuki Y., Yamasaki J., Suina K., Okazaki S., Koike N., Saya H, & Nagano O. (2019). Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT‐targeted therapy. Cancer Science, 111(1), 127-136.

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Quantification of Bile Acids and Dyes

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Hemin, bilirubin ditaurate and stercobilin HCl (mixture of isomers) were purchased from Frontier Scientific. Balsalazide disodium salt dihydrate, olsalazine sodium, sulfasalazine (all from Santa Cruz Biotechnology), salicylic acid (Sigma-Aldrich), diclofenac sodium salt (Sigma-Aldrich), meclofenamic acid sodium salt (MP Biomedicals), (±)-ibuprofen (Andeno B.V.), cromolyn sodium salt (Sigma-Aldrich), cetirizine 2HCl (AK-Scientific, Inc.), taurocholic acid sodium salt hydrate (Sigma-Aldrich), sodium glycocholate hydrate (Sigma-Aldrich), suramin sodium salt (Calbiochem), allura red AC (Sigma-Aldrich), tartrazine (Sigma-Aldrich) and 2-(ptoluidino)-6-naphthalenesulfonic acid potassium salt (TNS, Sigma-Aldrich) were used as supplied. Imatinib (free base) was a gift from the Vichem Chemie Research Ltd. (Budapest, Hungary). All other chemicals were of analytical reagent grade.

Zsila F., Kohut G, & Beke-Somfai T. (2019). Disorder-to-helix conformational conversion of the human immunomodulatory peptide LL-37 induced by antiinflammatory drugs, food dyes and some metabolites. International journal of biological macromolecules, 129.

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