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Umi780

Manufactured by United Imaging
Sourced in China

The UMI780 is a diagnostic imaging system designed for medical applications. It provides high-quality imaging capabilities for clinical use. The core function of the UMI780 is to capture and display medical images for diagnosis and treatment planning purposes.

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22 protocols using umi780

1

Lung CT Imaging Protocol for COVID-19 Diagnosis

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Each patient was placed in the supine position on the CT machine (uCT760 or Umi780, United Imaging, Shanghai, China; Precison32, Campo imaging, Shenyang, China) and scanned during the inspiratory phase. Images were reconstructed with a slice thickness of 1 mm and an interval of 1 mm.
Lung CT images were screened by three imaging physicians who were blind to the RT-PCR results and clinical information. The CT images were independently read by two radiologists with more than 5 years’ experience in the diagnosis of chest CT scans. In case of dispute, they discussed and reached a consensus that was reviewed by a senior imaging physician with more than 10 years of experience.
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2

Standardized CT Lung Imaging Protocol

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All scans were performed with patients in the supine position during end-inspiration without intravenous contrast on three CT scanners: uCT 760, uMI 780 scanners (United Imaging; Shanghai, China) and Precision 32 (CAMPO Imaging; Shenyang, China). Images were obtained from the apex to lung bases, using a standard dose protocol, reconstructed at 1.0 mm/1.1 mm slice thickness, with 0.7 mm increment, 512 × 512 mm and a sharp reconstruction kernel. The lung window width and level settings were 1500 Hounsfield units (HU) and −600 HU.
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3

Ga-68 PSMA-11 PET/CT Imaging Protocol

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PSMA-11(HBED-CC) was purchased from ABX (Germany). 68Ga-PSMA-11 was radiolabeled using the automated labeling module produced by ITM (Germany). The radiochemical purity was > 99%. The synthesis procedure was reported previously.[11 (link)] Whole-body PET/CT (uMI780, United Imaging, China) was performed from the vertex to the proximal legs 1 hour postinjection of 68Ga-PSMA-11 (111–185 MBq). Attenuation-corrected images were assessed clinically by certified nuclear medicine physicians.
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4

CT Lung Imaging Protocol

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All scans were performed with the patient in the supine position during end-inspiration without intravenous contrast on two CT scanners, uCT 760 and uMI 780 scanners (United Imaging). The scanning range was from the apex to lung base. All images were obtained with a standard dose scanning protocol, reconstructed at 1.0 mm slice thickness, with 1 mm increment, 512 mm × 512 mm, and a sharp reconstruction kernel (B_VSHARP_B). Lung window setting was with a window level of − 600 Hounsfield units (HU) and window width of 1500 HU.
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5

PET/CT Imaging Protocol for Cancer Evaluation

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From participating sites, we collected baseline 18F-FDG PET/CT images in the DICOM format. Patients with normal blood glucose levels were asked to fast, stop receiving intravenous glucose, and avoid severe activity or extended exercise for 6 h before intravenous 18F-FDG (3.7 MBq/kg) delivery. A hybrid PET/CT scanner (uMI780, United Imaging Healthcare, Shanghai, China) was used for all PET/CT imaging which included a low-dose CT scan (current 120 mA; tube voltage 120 kV; matrix 512 × 512 pixels; slice thickness 3.00 mm; window width 300–500 HU; window level 40–60 HU) and a PET scan (with 1.5 min/position in 3D acquisition mode and 5–6 bed positions), and it performed less than one hour after radiotracer injection as part of the scanning procedure. The PET image was reconstructed using attenuation iterative correction approach (Ordered Subsets Expectation Maximization, OSEM) and the window width and window level of the CT images were set to 350 and 50 then submitted to the MedEx workstation together with fusion imaging once all the patient's PET/CT image parameters had been standardized.
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6

Multimodal PET/CT Imaging Protocol

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For [18F]FDG PET/CT image acquisition, patients fasted for at least 6 hours and the plasma glucose level was lower than 11 mmol/L (about 200 mg/dL) (10 (link)). After an intravenous injection of [18F]FDG 3.7 MBq/kg, the patient rested in a quiet place. The patients were instructed to drink 500 mL of water to stimulate [18F]FDG excretion in the renal calyx and to urinate before scanning. Data were acquired using a PET/CT scanner (uMI780, United Imaging, Shanghai, China) 45 to 60 minutes after intravenous administration. First, a CT scan was performed from the head to the upper thigh (tube current of 120 mA, tube voltage of 120 kV, and slice thickness of 3.00 mm). PET was then performed at the same bed position as the CT scan, 5-6 bed positions, and 3D acquisition mode at 1.5 min/position. [68Ga]Ga-DOTA-FAPI-04 PET/CT was performed within 7 days of [18F]FDG PET/CT for comparison and the dose of [68Ga]Ga-DOTA-FAPI-04 injected was calculated based on patient body weight (1.85 MBq/kg). Other parameters of CT or PET were the same as [18F]FDG PET/CT, except that [68Ga]Ga-DOTA-FAPI-04 PET imaging was acquired at 3.0 min/position. After the reconstruction was complete, image analysis was performed using the joint imaging post-processing fusion software.
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7

Standardized 18F-FDG PET/CT Imaging Protocol

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Prior to the examination, all patients were mandated to fast for a minimum of 6 hours prior to examination. 18F-FDG was manufactured in line with standards set by our hospital, utilizing a 112-ring digital light guide PET/CT scanner (uMI780, United Imaging, China). The radiochemical purity was maintained at 98%, with the final products being diluted with saline and sterilized via a 0.22-μm Millipore filter through a sterile syringe. Doses of intravenously injected 18F-FDG were calculated utilizing each patient’s weight (3.7 MBq [0.1 mCi/kg]). The bounds for the images were set to CT scan from the head to upper thighs. PET scans were performed promptly post CT scan with 1.5 minutes of scanning time per image, utilizing 3-D mode for all images.
Two experienced nuclear medicine physicians (YW and JJW) examined all PET/CT images. For quantitative analysis, the SUVmax-PT was normalized to body weight and automatically calculated for the primary tumor. TLG-PT was calculated using SUVmean × MTV (metabolic tumor volume, whcih recorded at the absolute SUV threshold of 2.5 and the relative SUVmax-PT threshold of 70%). In the current study, we did not include SUVmax and TLG for the neck lymph nodes in the analysis, given that neck lymph node inflammation and the complex biology of lymph nodes may inadvertently influence the results of the research.23 (link)
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8

PET/CT Imaging of FAPI-04 Uptake

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The PET/CT scans were obtained 60 min after the intravenous injection of 111–185 MBq [68Ga]Ga-DOTA-FAPI-04. All PET/CT images were acquired from the head to the upper thighs. The CT scans were performed with a tube voltage of 120 kV, an effective tube current of 70–200 mAs (Dose Modulation (uMI780, United-Imaging Healthcare)), and a slice thickness of 3 mm. PET scans were immediately performed after the CT scan in 3D acquisition mode (matrix: 192×192) with 4–5 bed positions and 2 min/position. PET data were reconstructed iteratively (2 iterations and 20 subsets) with CT data for attenuation correction, and the PET/CT images were then coregistered and displayed using dedicated software (Image Fusion software, UIH).
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9

Detailed PET/CT Imaging Protocol

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All images were acquired with a digital PET/CT scanner (uMI780, United Imaging Healthcare, Shanghai, China) equipped with lutetium–yttrium orthosilicate crystal coupled with silicon (Si) photomultipliers (PM). The patients were asked to fast a least 6 h before the PET/CT examination. The patients received an injection of the 18F-FDG solution according to their body weight (5.0 MBq/kg). The PET/CT examination was started 60 min after the injection. The phantom and the patients underwent a CT scan using a tube voltage of 120 kVp and a tube current of 250 mAs with automatic modulation, followed by a whole-body PET scan with an emission time of 2 min per bed position from the skull base to the upper thigh of the patient or about 30 cm long to cover the whole phantom.
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10

PET/CT Imaging of COVID-19 Patients

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Patients were asked to fast for a minimum of six hours prior to PET/CT scans. PET/CT imaging was conducted via a 112-ring digital light guide PET/CT (uMI780, United Imaging, China) according to published guidelines for PET/CT imaging 12 (link). Helical CT was implemented from the head to proximal thigh prior to PET procurement based on the standardized protocol. Static acquisitions from head to proximal thigh were obtained 45 minutes post 18F-FDG injection and lasted for a period of 15 minutes. Dynamic acquisitions were done as follows: imaging started at the time of injection of 18F-FDG (3.75 MBq/kg produced from Guangzhou Atom High Tech Radiopharmaceutical Co.,Ltd., Guandong Province, China) and continued for 60 minutes. Dynamic scans were conducted from the lung apex to the liver for the COVID-19 group and control group 2. Each dynamic PET study lasted 60 minutes that contained 48 frames (time × frame: 5s × 18, 10s × 6, 30s × 5, 60s × 5, 150s × 8, 300s × 6) and was adjusted for isotope decay, scattering events, and random coincidence.
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