7t magnetom system

Manufactured by Siemens

Sourced in Germany

The 7T Magnetom system is a high-field magnetic resonance imaging (MRI) scanner developed by Siemens. It operates at a magnetic field strength of 7 tesla, which is significantly higher than the commonly used 1.5T and 3T MRI systems. The 7T Magnetom system is designed to provide high-resolution imaging of the human body, enabling detailed visualization of anatomical structures and physiological processes.

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Lab products found in correlation

Trio system, by Siemens (1 mentions) 32 channel head coil, by Siemens (1 mentions) Nova medical head coil, by Siemens (1 mentions)

Close spelling variants of this product

Magnetom 7T (64 citations) Magnetom 7T MRI system (5 citations)

5 protocols using 7t magnetom system

Multi-modal Neuroimaging Acquisition Protocol

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Functional MRI data were acquired using a Siemens 7T Magnetom system with a 32-channel head coil. Blood oxygenation level dependent (BOLD) fMRI was acquired using a T2*-weighted multislice gradient echo planar imaging (EPI), with true axial slices centered on the left anatomical hand knob in the z-axis (TR 1500 ms, TE 25 ms, slice thickness 1.2 mm, in-plane resolution 1.2 × 1.2 mm, 22 axial slices, GRAPPA factor = 2). One single volume contrast matched EPI acquisition of the same resolution was also acquired for registration purposes. fMRI data acquisition, task and data preprocessing have been detailed previously (Kolasinski et al., 2016 (link)).
Structural MRI data were acquired using a 3T Siemens Trio system during one of the scan sessions with a multi-echo magnetisation prepared rapid acquisition gradient echo (MEMPRAGE) sequence (van der Kouwe et al., 2008 (link)) (TR 2530 ms, TE 1.69, 3.55, 5.41 and 7.27 ms, slice thickness 1.0 mm, in-plane resolution 1.0 × 1.0 mm, GRAPPA factor = 2).

Kolasinski J., Makin T.R., Logan J.P., Jbabdi S., Clare S., Stagg C.J, & Johansen-Berg H. (2016). Perceptually relevant remapping of human somatotopy in 24 hours. eLife, 5, e17280.

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High-Field fMRI with Physiological Monitoring

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The measurements were performed with a 7 T MAGNETOM system (Siemens Healthcare, Erlangen, Germany) using a 32 channel Nova Medical head coil (Wilmington, USA). 140 volumes were acquired per run using an optimized multiband EPI sequence with 30 coronal slices parallel to the floor of the IVth ventricle (TR/TE = 1000/23 ms, multiband factor = 2, in-plane acceleration = GRAPPA 2, echo spacing = 0.81 ms, bandwidth = 1450 Hz/Px, FOV 220 × 220 mm, 1.46 × 1.46 mm in-plane resolution, 1.5 mm slice thickness, 15% gap, with the phase-encoding direction being foot-to-head). B₀ field maps were acquired before the functional scans with the same slice prescription as the EPI sequence using a multi-echo gradient-echo (MGE) sequence (TR 800 ms, TE 5, 10, 16 ms). Cardiac and respiratory waveforms were recorded using Siemens Bluetooth Physiological Monitors. For the pulse oximetry (PO), a photoplethysmograph with an infra-red emitter was placed on the left index finger. The respiratory sensor was attached to a pneumatic belt wrapped around the abdomen and was placed medially beneath the diaphragm. PO and respiration were both recorded at a sampling frequency of 50 Hz and were time-locked to the first volume acquired in each run.

Matt E., Fischmeister F.P., Amini A., Robinson S.D., Weber A., Foki T., Gizewski E.R, & Beisteiner R. (2019). Improving sensitivity, specificity, and reproducibility of individual brainstem activation. Brain Structure & Function, 224(8), 2823-2838.

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Multimodal Brain Remyelination Imaging

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A subset of 22 participants (11 active and 11 control group) will undergo an optional MRI at baseline and 24 weeks as an exploratory outcome measure of structural remyelination of the brain. Whole brain MPRAGE images will be acquired on a 7T MAGNETOM system (Siemens, Erlangen, Germany) using a 24-channel array RF coil (Nova Medical, Wilmington, Massachusetts, USA) for co-registration and planning purposes (TI/TE/TR/α/data matrix/res=1.05 s/3.1 ms/2.2 s/7°/320×320×240/0.7 mm isotropic). A highly sampled inversion recovery (IR) technique—progressively unsaturated relaxation during perturbed recovery from inversion sequence with 32 inversion time points will be implemented to acquire 5 mm thick slices (TI/TE/TR/α/data matrix/res=0.017 8.0 s/7 ms/14.0 s/5°/128×128; (2 mm in-plane)). We will segment white matter structures (the corpus callosum and bilateral internal capsules) and MS lesions superior to the tentorium cerebelli. A multiexponential fitting procedure will be used on a voxel-wise basis to decompose IR recovery curves into short and long T components. The short T₁ component will be assigned to myelin associated water, and its amplitude will be used to calculate MWF. Tissue water content will be quantified and used to correct MWF. No contrast agent will be administered.

Wooliscroft L., McCoy S., Hildebrand A., Rooney W., Oken B.S., Spain R.I., Kuehl K.S., Bourdette D, & Cameron M. (2023). Protocol for an exploratory, randomised, single-blind clinical trial of aerobic exercise to promote remyelination in multiple sclerosis. BMJ Open, 13(1), e061539.

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Multi-modal Brain Imaging at 7T

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Data were acquired in 3 healthy volunteers (2 male), with informed consent in accordance with local ethics, on a whole‐body 7T Magnetom system (Siemens Healthineers, Erlangen, Germany) using a transmit/receive head coil with single channel transmit and 32 receive channels (Nova Medical, Wilmington MA, USA). Isotropic slab acquisitions were performed on all subjects, whereas whole‐brain anisotropic data were acquired in only 2 of the subjects. For structural comparison, 0.7 mm isotropic MPRAGE data were acquired in all subjects.
The functional data (isotropic slab and anisotropic whole‐brain) were acquired in 5‐min runs of a 30 s off/on task consisting of an 8 Hz modulated flashing checkerboard (visual slab), bilateral finger tapping (motor slab), or simultaneous checkerboard and fingertapping (whole brain). Head motion was mitigated using padding inside the head coil, and subjects were instructed to remain as still as possible during scanning.

Graedel N.N., Miller K.L, & Chiew M. (2022). Ultrahigh Resolution fMRI at 7T Using Radial‐Cartesian TURBINE Sampling. Magnetic Resonance in Medicine, 88(5), 2058-2073.

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Healthy Brain Imaging at 7T

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All data were measured using a Siemens 7T MAGNETOM system (Siemens Medical Systems, Erlangen, Germany) equipped with a 70 mT/m gradient coil with maximal slew rate of 200 T/m/s and a 32 channel head coil. We measured three healthy male volunteers who gave written informed consent prior to participation. All volunteers had no self-reported history of any psychiatric or neurological diseases and did not suffer from any brain injuries.
The study was approved by the local ethical committee.

Maximov I.I, & Vellmer S. (2019). Isotropically weighted intravoxel incoherent motion brain imaging at 7T. Magnetic resonance imaging, 57.

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