Discovery mr750 mri scanner

Manufactured by GE Healthcare

Sourced in United States

The Discovery MR750 is a magnetic resonance imaging (MRI) scanner manufactured by GE Healthcare. It is designed to capture high-quality images of the body's internal structures and functions. The scanner utilizes strong magnetic fields and radio waves to generate detailed images, which can be used for diagnostic purposes by healthcare professionals.

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Lab products found in correlation

32 channel head coil, by GE Healthcare (1 mentions) 32 channel nova head coil, by GE Healthcare (1 mentions) Discovery mr750w scanner, by GE Healthcare (1 mentions) 8 channel head coil, by GE Healthcare (1 mentions) Presentation software, by Neurobehavioral Systems (1 mentions) 306 channel whole head meg system, by Elekta (1 mentions)

9 protocols using discovery mr750 mri scanner

Pseudo-Continuous ASL MRI Acquisition

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MRI was completed on a 3 T MR 750 Discovery™ MRI scanner (GE healthcare, Milwaukee, USA) with a 32‐channel head coil at the Oslo University Hospital, Oslo, Norway.
We applied a Pseudo‐Continuous ASL (PCASL) sequence with images obtained with an interleaved 3D spiral fast spin echo (FSE) readout module. Scan time was 4:55 min, with the following parameters: 512 sampling points on eight spirals, spatial resolution = 4 × 4 × 3 mm, default reconstructed spatial resolution = 2 × 2 × 3 mm, TR = 5025, TE = 11,072 ms, labeling duration = 1450 ms, post‐labeling delay = 2025 ms, slice thickness = 3 mm, number of slices = 104, number of excitations = 3, and FOV = 256 mm. Care was taken when placing the lower edge of the 3D slab just below the cerebellum, which ensured that the distance to the labeling plane was approximately 9 cm below the anterior commissure to posterior commissure (AC‐PC) line, in head to feet direction (Aslan et al., 2010 (link)).
Structural T1‐weighted MRI were acquired using an inversion recovery‐fast spoiled gradient echo (BRAVO) sequence with 188 sagittal slices. Scan time was 4:43 min, TE = 3.18 ms, TR = 8.16 ms, T1 = 450 ms, field of view (FOV) = 256 mm, acquisition matrix = 256 × 256, 1 mm³ isotropic voxels, flip angle (FA) = 12°.

Sanders A., Richard G., Kolskår K., Ulrichsen K.M., Alnæs D., Beck D., Dørum E.S., Engvig A., Lund M.J., Nordhøy W., Pedersen M.L., Rokicki J., Nordvik J.E, & Westlye L.T. (2023). Associations between everyday activities and arterial spin labeling‐derived cerebral blood flow: A longitudinal study in community‐dwelling elderly volunteers. Human Brain Mapping, 44(8), 3377-3393.

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3T MRI Imaging with Custom Coil

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Imaging was performed in a 3-Tesla GE MR 750 Discovery MRI scanner (GE Healthcare, Waukesha, WI) as previously described¹⁶. A custom 3-inch diameter, receive-only surface coil (MR Instruments, Inc., Minneapolis, MN) was used for scanning.

Brady M.L., Raghavan R., Block W., Grabow B., Ross C., Kubota K., Alexander A, & Emborg M.E. (2015). The relation between catheter occlusion and backflow during intraparenchymal cerebral infusions. Stereotactic and functional neurosurgery, 93(2), 102-109.

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High-Resolution Brain Imaging Protocol

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Scanning was conducted on a 3T General Electric MR750 Discovery MRI scanner at the Center for Functional MRI (University of California, San Diego) using a NOVA 32 channel head coil. Functional images were acquired using a gradient- echo, echo-planar, T2*-weighted pulse sequence, using parameters closely matched to the HCP Lifespan brain imaging protocol (800 msec TR; 37.0 msec TE; 104 × 104 matrix size; 20.8 cm field of view; 2 mm × 2 mm in-plane resolution; multiband acceleration factor = 8). Seventy-two axial slices (slice thickness = 2 mm) were acquired covering the whole brain. Spin-echo fieldmap scans with opposite phase encoding directions (P > A and A > P) were acquired for susceptibility induced distortion correction after run 1 to correct functional runs 1–3 and after run 4 to correct functional runs 4–6. Following the third functional run, high-resolution structural images were acquired using a sagittal T1-weighted MPRAGE pulse sequence (25.6 cm field of view; 160 slices; 1 mm slice thickness; 256 × 256 matrix size). PROMO (PROspective MOtion correction; White et al., 2009 (link)) was used to adaptively compensate for motion during structural scanning resulting in no loss of anatomical data due to subject motion.

Tallman C.W., Luo Z, & Smith C.N. (2024). Human brain activity and functional connectivity associated with verbal long-term memory consolidation across 1 month. Frontiers in Human Neuroscience, 18, 1342552.

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Childhood Brain MRI Characterization

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For the current study, we investigated MRI data from children enrolled in the
Generation R Study.^{8 (link)} Three waves of MRI examinations were performed within this population-based
cohort: phase 1: a subgroup of children between the ages of 6 and 10,^{9 (link)} the whole study group in phase 2: children around 9 years,^{10 (link)} and phase 3: children around 13 years. Participants were imaged with a 3T MRI
scanner: the first subgroup (6–10 years) with an MR750 Discovery MRI scanner and the
other two groups (around 9 and 13 years) with an MR750w Discovery scanner (General
Electric, Milwaukee, WI, USA). The imaging protocol encompassed, among others, a
coronal 3-dimensional (3D) T₁-weighted sequence, sagittal 3D
T₂-weighted sequence, and axial spin-echo diffusion-weighted
sequence. No gadolinium was administered due to the population-based design of the
study. Incidental findings were rated by a team of researchers and neuroradiologists
as previously described.^{11 (link)} RIS was assessed with adult Okuda criteria and pediatric criteria proposed by
the PARIS consortium.^{1 (link),4}Parents or legal representatives provided written informed consent of all study
participants within the Generation R study. Identified RIS cases provided additional
informed consent for the usage of clinical data. The Medical Ethical Committee of
the Erasmus Medical Center approved the study protocol.

de Mol C., Bruijstens A., Jansen P., Dremmen M., Wong Y., van der Lugt A., White T, & Neuteboom R. (2021). Prevalence of radiologically isolated syndrome in a pediatric population-based cohort: A longitudinal description of a rare diagnosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 27(11), 1790-1793.

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Sparse-Sampling fMRI Protocol for Noise-Free Imaging

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Imaging data were acquired using a 3T GE Discovery MR750 MRI Scanner and an 8-channel head coil for radio frequency reception (General Electric, Milwaukee Wisconsin, USA). Sagittal T-1 weighted localizer images were acquired and used to define a volume for data collection and high order shimming. A semi-automated high-order shimming program was used to ensure global field homogeneity. High resolution anatomical images were collected using a 3D FSPGR sequence (voxel size = 1.0 mm³, FoV = 256 mm, TR = 7.156 ms, TE = 2.112 ms, TI = 450 ms, flip angle = 12°, number of slices = 162, sense factor = 2). Three runs of functional data using a sparse-sampling, inverse-spiral technique were also collected (voxel size = 3.75 × 3.75 × 3.8 mm, FoV = 240 mm, TR = 3000 ms, TE = 28 ms, flip angle = 90°, 42 contiguous oblique axial slices parallel to the AC-PC line, interleaved slice acquisition, 116 volumes per run, 2 disdaqs, 5.8 minutes per run). A sparse-sampling technique was used during the functional runs to eliminate scanner noise while the stimuli were being displayed. This method introduces periods of silence between volume acquisitions. Thus, for each trial in this study, there was a 1.5-second silent period that corresponded to the presentation of the 1.5-second video clip, prior to each 1.5-second data collection period.

Diaz M.T, & Yalcinbas E. (2021). The neural bases of multimodal sensory integration in older adults. International journal of behavioral development, 45(5), 409-417.

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Functional Brain Imaging and Behavioral Responses

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Functional images were acquired with a Discovery MR750 MRI scanner (General Electric, Milwaukee, WI, USA) operating at 3 Tesla in the University Hospital of Parma, Italy. The imaging parameters were as follows: repetition time (TR), 2500 ms; echo time (TE), 30 ms; acceleration factor 2, bandwidth 3906 Hz/PIXEL matrix 96 × 96, field of view (FOV), 205 × 205 mm²; 41 contiguous slices were acquired in interleaved order, slice thickness, 2.8 mm + 0.7 mm gap. The imaging parameters for the 3D IR-prepared FSPGR T1-weighted anatomical scan were as follows: TR, 8500 ms; TE, 3.2 ms; FOV, 256 × 256 mm²; matrix 256 × 256; slice thickness, 1 mm; total slices, 156, bandwidth 244 Hz/PIXEL.
The stimuli were presented with a head-mounted VisualStim system goggles (Resonance Technology, San Diego, CA, USA) with a screen resolution of 800 × 600 pixels and surrounded by a black background. A fiber optic Response Box device was used to measure the responses (Resonance Technology, San Diego, CA, USA). The participants were asked to use their index and the middle fingers to answer by pressing two buttons. The stimuli presentation and the responses collection were done using the Presentation software (Neurobehavioral Systems, CA, USA).

Park S.A., Sestito M., Boorman E.D, & Dreher J.C. (2019). Neural computations underlying strategic social decision-making in groups. Nature Communications, 10, 5287.

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Tower of London Task in 3T MRI Scanning

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The following sequences were collected on a 3 T Discovery MR750 MRI scanner (GE Medical Systems) with a 12-channel head coil: a 3-dimensional fast spoiled gradient echo imaging structural scan (repetition time 8.184 ms, echo time 3.192 ms, matrix 256 × 256 mm, 182 slices, voxel size 1 × 1 × 1 mm); a field map to account for B₀ distortions; and functional gradient echo-planar images (repetition time 2000 ms, echo time 25 ms, field of view = 256, matrix 96 × 96, 41–43 interleaved slices per volume, 3 × 3 mm in-plane resolution, slice thickness 3 mm, interslice gap 1 mm). The number of volumes for each Tower of London run was 260, for a total of 520 volumes pre-SPT and 520 volumes post-SPT. We used sagittal acquisition for all scans because it displayed the lowest amount of signal dropout over ventromedial prefrontal cortical structures during piloting. A pediatric neuroradiologist found no clinically relevant incidental findings in the structural scans.

Jaspers-Fayer F., Lin S.Y., Best J.R., Thorsen A.L., Negreiros J., Chan E., Ellwyn R., Lin B., de Wit S., van den Heuvel O.A, & Stewart S.E. (2022). An fMRI study of cognitive planning before and after symptom provocation in pediatric obsessive–compulsive disorder. Journal of Psychiatry & Neuroscience : JPN, 47(6), E409-E420.

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Multimodal Brain Imaging Using MEG and MRI

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The continuous neuromagnetic signal was recorded using a 306-channel, whole-head MEG system (Elekta-Neuromag TRIUX, Helsinki, Finland) at Peking University. Before each block started, the head position of each subject was determined by four head-position indicator (HPI) coils. The electrooculogram (EOG) signal was simultaneously captured by two electrodes placed near the eyes as follows: one electrode was placed above the right eye, and one electrode was placed below the left eye. The continuous MEG data were on-line bandpass filtered at 0.1–330 Hz. The sampling rate was 1000 Hz.
The subjects’ structural MRI images were obtained with a 3T GE Discovery MR750 MRI scanner (GE Healthcare, Milwaukee, WI, USA). A three-dimensional (3D) fast gradient-recalled acquisition in the steady state with a radiofrequency spoiling (FSPGR) sequence was used to obtain 1 × 1 × 1 mm³ resolution T1-weighted anatomical images. We co-registered the MEG data with the MRI data based on the location of three fiducial marks (the nasion and two pre-auricular points) and approximately 150 digitalization points on each subject’s scalp.

Lu L., Wang Q., Sheng J., Liu Z., Qin L., Li L, & Gao J.H. (2019). Neural tracking of speech mental imagery during rhythmic inner counting. eLife, 8, e48971.

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Structural Brain Imaging Analysis with MRI

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MRI was used to measure structural neuroimaging outcomes within the SAMS CU cohort. Data were acquired on a 3T GE Discovery MR750 MRI scanner (GE Healthcare) using a 32‐channel radiofrequency receive‐only head coil (Nova Medical). For the current analyses, we processed a whole‐brain high‐resolution T1‐weighted anatomic volume (repetition time [TR] = 7.26 ms, field of view [FoV] = 230 mm × 230 mm, voxel size = 0.9 × 0.9 × 0.9 mm, slices = 186), through FreeSurfer version 7. Subcortical and cortical region of interest (ROI) volumes—including total gray matter, hippocampus, and white matter hypointensity volume—were defined by FreeSurfer's aparc+aseg atlas.

Abiose O., Rutledge J., Moran‐Losada P., Belloy M.E., Wilson E.N., He Z., Trelle A.N., Channappa D., Romero A., Park J., Yutsis M.V., Sha S.J., Andreasson K.I., Poston K.L., Henderson V.W., Wagner A.D., Wyss‐Coray T, & Mormino E.C. (2023). Post‐translational modifications linked to preclinical Alzheimer's disease–related pathological and cognitive changes. Alzheimer's & Dementia, 20(3), 1851-1867.

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