Ge signa 3t scanner

Manufactured by GE Healthcare

Sourced in United States

The GE Signa 3T scanner is a magnetic resonance imaging (MRI) system that operates at a field strength of 3 Tesla. It is designed to provide high-quality imaging for a variety of clinical applications.

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Lab products found in correlation

Somatom sensation 16, by Siemens (1 mentions)

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Signa scanner (128 citations) 3T scanner (86 citations) GE Signa (42 citations) GE Signa scanner (37 citations) Signa 3T scanner (23 citations) Signa 3T (20 citations) 3T GE scanner (14 citations) GE scanners (10 citations) Scanners (2 citations)

7 protocols using ge signa 3t scanner

Multimodal brain imaging across sedation

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Structural and rs-fMRI data were acquired using a whole-body 3T Signa GE scanner (GE Healthcare, Waukesha, WI, USA) with a standard 32-channel transmit-receive head coil. Functional imaging data were acquired during each of four 15-minute scans in wakefulness, light sedation, deep sedation, and recovery, respectively, with repetition time (TR), 2 s; total volumes, 450; echo time, 25 ms; slice thickness, 3.5 mm; in-plane resolution, 3.5 × 3.5 mm; number of slices, 41; flip angle, 77°; field of view, 22.4 cm; matrix size, 64 × 64. High-resolution three-dimensional spoiled gradient-recalled echo axial images were acquired before functional scans with TE/TR/TI, 3.2/8.2/450 ms; slice thickness, 1 mm; 150 slices; flip angle, 12°; field of view, 24 cm; matrix size, 256 × 256.

Liu X., Lauer K.K., Ward B.D., Roberts C.J., Liu S., Gollapudy S., Rohloff R., Gross W., Xu Z., Chen S., Wang L., Yang Z., Li S.J., Binder J.R, & Hudetz A.G. (2019). Regional entropy of functional imaging signals varies differently in sensory and cognitive systems during propofol-modulated loss and return of behavioral responsiveness. Brain imaging and behavior, 13(2), 514-525.

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Multimodal Brain Imaging in Research

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Resting-state structural and fMRI data were acquired using a whole-body 3T Signa GE scanner (GE Healthcare, Waukesha, Wisconsin, USA) with a standard transmit-receive head coil. Functional imaging BOLD signals were obtained during a 7-min scan for each subject using the following sequence parameters: repetition time, 2 s; echo time, 25 ms; total volumes, 210; slice thickness, 4.0 mm; in-plane resolution, 3.75 × 3.75 mm; number of slices, 39; ip angle, 90°; eld of view, 24.0 cm; matrix size, 64 × 64. High-resolution three-dimensional spoiled gradient-recalled echo axial images were acquired before functional scans with TE/TR/TI, 3.2/8.2/450 ms; slice thickness, 1 mm; 188 slices; ip angle, 7°; eld of view, 256 mm; matrix size, 256 × 256.

Chen S., Wang Y., Meng X., Yang Z., Weng D., Wu X., & Wang L. (2021). Information Content Carried by Brain Signals Reduces Differentially in MCS and UWS Patients.

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3T fMRI Acquisition Protocol

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Blood oxygen level-dependent (BOLD) fMRI was performed on a GE Signa 3T scanner (GE Healthcare) equipped with a standard quadrature head coil. A gradient-echo planar imaging sequence (repetition time, 2000 ms; echo time, 30 ms; thickness, 4 mm; gap, 1 mm; flip angle, 90°; field of view, 24 cm; and matrix, 64 × 64) was used to acquire images while the subjects performed the tasks (N-back: 120 volumes for each run, 20 interleaved axial slices; VAC: 300 volumes, 26 interleaved axial slices). The first four scans were discarded to allow for T1 equilibration effects.

Fazio L., Logroscino G., Taurisano P., Amico G., Quarto T., Antonucci L.A., Barulli M.R., Mancini M., Gelao B., Ferranti L., Popolizio T., Bertolino A, & Blasi G. (2016). Prefrontal Activity and Connectivity with the Basal Ganglia during Performance of Complex Cognitive Tasks Is Associated with Apathy in Healthy Subjects. PLoS ONE, 11(10), e0165301.

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Functional Magnetic Resonance Imaging of Visual Attention

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Blood oxygen level-dependent (BOLD) fMRI was performed on a GE Signa 3T scanner (General Electric, Milwaukee, WI) equipped with a standard quadrature head coil. A gradient-echo planar imaging sequence (repetition time: 2000 ms; echo time: 28 ms; 26 interleaved axial slices; thickness: 4 mm; gap: 1 mm; voxel size: 3.75 isotropic; scan repetition: 300; flip angle: 90°; field of view: 24 cm; matrix: 64 × 64) was used to acquire images while subjects performed the VAC task. The first four scans were discarded to allow for signal saturation. Images for each subject were realigned, spatially normalized into the MNI template (12-parameter affine model), and spatially smoothed (10-mm Gaussian filter). After realignment, datasets were also checked for small-motion correction (<2 mm in translation, <1.5° in rotation).

Taurisano P., Romano R., Mancini M., Giorgio A.D., Antonucci L.A., Fazio L., Rampino A., Quarto T., Gelao B., Porcelli A., Papazacharias A., Ursini G., Caforio G., Masellis R., Niccoli-Asabella A., Todarello O., Popolizio T., Rubini G., Blasi G, & Bertolino A. (2014). Prefronto-striatal physiology is associated with schizotypy and is modulated by a functional variant of DRD2. Frontiers in Behavioral Neuroscience, 8, 235.

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Subdural Electrode Implantation for Intractable Epilepsy

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Prior to the study, all subjects submitted written consent for participating in the study. This study was approved by the Institutional Review Board of the Seoul National University Hospital (IRB No. H-0912-067-034). Five subjects (three females and two males, aged 25–37 years) with intractable epilepsy participated in the present study. All patients underwent implantation of subdural electrodes for clinical purposes. The clinical demography of the patients is presented in Table 1. Computed tomography (CT, Siemens SOMATOM sensation16, Siemens medical solution, Erlangen, Germany) for each subject was carried out before and after implantation of the subdural electrodes. Magnetic resonance images (MRIs, GE Signa 3T scanner, GE medical system, Milwaukee, Wisconsin) were also acquired after the implantation.

Kim K., Kim J.S, & Chung C.K. (2017). Increased Gamma Connectivity in the Human Prefrontal Cortex during the Bereitschaftspotential. Frontiers in Human Neuroscience, 11, 180.

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Intracranial EEG and Electrical Stimulation Mapping

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All subjects underwent extraoperative intracranial EEG monitoring as well as ESM as part of clinical management [1 (link)], [2 (link)], [20 (link)]. Subdural electrode pairs were stimulated with a pulse-train of 5 s maximum duration, a pulse width of 0.3 ms, a frequency of 50 Hz, and an intensity ranging from 3 to 9 mA. Electrode sites where stimulation consistently induced contralateral body movement of face, hand, and foot, expressive aphasia during auditory naming task, expressive aphasia during visual naming task, receptive aphasia during auditory naming task, speech arrest, visual phosphene (lower-order visual areas), and visual distortion (higher-order visual areas) were defined as eloquent functions of interest. The procedure of ESM recording is described in detail in our previous study [21 (link)].
DWI data were acquired using a GE Signa 3T scanner (GE Healthcare, Milwaukee, WI) equipped with an 8-channel head coil at TR = 12500 ms, TE = 88.7 ms, FOV = 24 cm, 128 × 128 acquisition matrix, contiguous 3 mm slice thickness, 55 isotropic gradient directions with b = 1000 s/mm², and single b = 0 acquisition. T1-weighted structural images were also acquired using a 3D fast spoiled gradient echo sequence (FSPGR) at TR = 9.12 ms, TE = 3.66 ms, TI = 400 ms, slice thickness = 1.2 mm, and planar resolution = 0.94 × 0.94 mm².

Lee M.H., Sonoda M., Kuroda N., O’Hara N., Dong M., Juhasz C., Asano E, & Jeong J.W. (2020). Novel Deep Learning Network Analysis of Electrical Stimulation Mapping-driven Diffusion MRI Tractography to Improve Preoperative Evaluation of Pediatric Epilepsy. IEEE transactions on bio-medical engineering, 67(11), 3151-3162.

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Whole-Brain Imaging Protocol for fMRI

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Whole-brain imaging data were acquired on a GE-Signa 3-T scanner (General Electric, Milwaukee, WI) at the University of Georgia Bio-Imaging Research Center (birc.uga.edu). A total of 195 functional images were acquired using a gradient echo T2*-weighted echoplanar imaging scan and were obtained using a flip angle of 90°, repetition time = 2.0 s, echo time = 25 ms, 40 slices, and field of view = 220 × 64 mm matrix. For the structural whole-brain images, a three-dimensional highresolution spoiled gradient scan was conducted (repetition time, 24 ms; echo time, 4.5 ms; flip angle, 20°; matrix size, 256 × 256; field of view, 25.6 cm; slice thickness, 1.0 mm; 164 contiguous slices).

Filkowski M.M., Anderson I.W, & Haas B.W. (2016). Trying to trust: Brain activity during interpersonal social attitude change. Cognitive, affective & behavioral neuroscience, 16(2).

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