All drugs—borneol, carbamazepine, phenytoin, phenobarbital and valproate—were purchased from Sigma-Aldrich (Poznań, Poland). scoparone was isolated from Artemisia umbelliformis Lam. (Asteraceae), as reported previously [19 (link)]. All the studied drugs, except for valproate (i.e., borneol, scoparone, carbamazepine, phenobarbital and phenytoin), were suspended in a 1% aqueous solution of Tween 80 (Sigma-Aldrich, Poznań, Poland), while valproate was dissolved in distilled water. The ASMs were administered intraperitoneally (ip) as follows: phenytoin—120 min, phenobarbital—60 min and carbamazepine and valproate—30 min, before the experiments, as reported earlier [39 (link),40 (link)]. borneol and scoparone were injected i.p. at increasing time periods of 15, 30, 60 and 120 min. Of note, these pretreatment times for borneol and scoparone when used separately (i.e., 15, 30, 60 and 120 min.) were based on our previously published work in order to make the results for scoparone comparable to those for other coumarins (i.e., osthole, imperatorin and xanthotoxin) tested earlier [10 (link),26 (link)]. For all the combinations with ASMs, both borneol and scoparone were administered i.p. 15 min. before the MES test and brain tissue sampling.
Carbamazepine
Manufactured by Merck Group
Sourced in United States, Germany, United Kingdom, Poland, Switzerland, Italy, Spain
Carbamazepine is a chemical compound used as a reference standard in analytical testing procedures. It is a white, crystalline powder that is commonly used to verify the accuracy and precision of analytical equipment and methods.
Automatically generated - may contain errors
Lab products found in correlation
Ibuprofen, by Merck Group (18 mentions)
Methanol, by Merck Group (18 mentions)
Diclofenac, by Merck Group (18 mentions)
Acetonitrile, by Merck Group (17 mentions)
Sulfamethoxazole, by Merck Group (16 mentions)
Caffeine, by Merck Group (16 mentions)
Formic acid, by Merck Group (16 mentions)
Atenolol, by Merck Group (13 mentions)
Acetaminophen, by Merck Group (13 mentions)
Phenytoin, by Merck Group (12 mentions)
Propranolol, by Merck Group (10 mentions)
Phenobarbital, by Merck Group (10 mentions)
Indomethacin, by Merck Group (9 mentions)
Ketoprofen, by Merck Group (9 mentions)
Naproxen, by Merck Group (9 mentions)
Metoprolol, by Merck Group (9 mentions)
Clonazepam, by Merck Group (9 mentions)
Dimethyl sulfoxide (dmso), by Merck Group (9 mentions)
Trimethoprim, by Merck Group (8 mentions)
Ethosuximide, by Merck Group (8 mentions)
168 protocols using carbamazepine
1
Anticonvulsant Interactions: Borneol and Scoparone
2
Modulation of Autophagy in Oyster Spat
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Three treatments were used to test the modulation of autophagy in oyster spat. Groups of spat were maintained for 24 or 48 h in seawater supplemented with dissolved (1) NH4Cl (Sigma-Aldrich, A9434) at a concentration of 0.53 g/10 L of seawater, (2) carbamazepine (Sigma-Aldrich, C4024) at a concentration of 0.071 g/10 L seawater, or (3) carbamazepine+NH4Cl at concentrations of, respectively, 0.071 g/10 L of seawater and 0.53 g/10 L of seawater [12 ]. One control condition was also used, which consisted of spat maintain only in the seawater. For each of the 4 conditions tested (3 treatments and 1 control), 6 tanks were used containing 13 oysters each. At each sampling time (24 and 48 h), 3 tanks of 13 animals were sampled per condition. At T0 (the time before oysters were incubated in the different test conditions), 3 pools of 13 oysters were sampled to record the basal level of autophagy in their hemocytes.
3
Mood Stabilizers and HDAC Inhibitors Influence FGF21 in C6 Cells
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
C6 cells (American Type Culture Collection, Manassas, VA), with a passage number of 45, were cultured in Dulbecco’s Modified Eagle’s Medium supplemented with 10% fetal bovine serum and incubated at 37°C in a humidified atmosphere containing 5% CO2 and 95% air. Cells grown in 60-mm plates to 60% to 70% confluence were treated with mood stabilizers VPA, lithium, lamotrigine, carbamazepine, and HDAC inhibitors SB, PB, MC1568 (MC), SAHA, TSA, entinostat (MS275), apicidin, mocetinostat (Moce), or romidepsin (FK228) for 24 hours and then harvested for FGF21 mRNA analysis (VPA, lithium, lamotrigine, carbamazepine, SB, PB, SAHA, and TSA obtained from Sigma-Aldrich; MS275, apicidin, Moce, and FK228 obtained from Selleckchem). Cells grown on 25-mm circular glass cover slips were treated with the above drugs for 24 hours and stained with 0.5 μM calcein AM (Thermo Fisher Scientific), which emits a green color for live cell staining, and 5 μg/ml Hoechst 33258 (Sigma-Aldrich), which yields a blue color for cell nuclear staining (Zhu et al., 2002 (link)).
4
Pharmaceutical Compounds Characterization
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Paracetamol, carbamazepine, and indomethacin were kindly provided by Merck KGaA, Darmstadt, Germany. N,N-Dimethylformamide, ethanol (HPLC grade), methanol (HPLC grade), acetone, and dimethyl sulfoxide (DMSO) (HPLC grade) were purchased from Bio-Lab Ltd., Jerusalem, Israel.
5
Synthesis of Yttrium-Doped Titanium Dioxide
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Titanium(IV) chloride (97%), urea (p.a.), yttrium(III) chloride hexahydrate (99%), ammonium oxalate (99%), silver nitrate (> 99%), tert-butyl alcohol (99%) benzoquinone (p.a,), and carbamazepine (analytical standard) were purchased from Merck. All reagents were of analytical grade and used without any further purification. The water used in all experiments was deionized.
6
Quantifying Pharmaceutical Contaminants
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The target pharmaceutical compounds in this study were carbamazepine, ibuprofen, ciprofloxacin, sulfamethoxazole, erythromycin and clarithromycin, and were purchased from Merck Millipore (Gauteng, South Africa). The target compounds were selected based on global use. The standard solution (1000 µg/mL) of the target compounds were prepared by dissolving the weighed standard powder into methanol (High Performance Liquid Chromatography gradient-grade) purchased from Merck Millipore (Gauteng, South Africa). The structure and molecular weight of the target pharmaceuticals are shown in Table 2 .
7
Photocatalytic Degradation of Organic Pollutants
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The reactions were performed on a Heidolph MR Hei-Tec, equipped with Radleys Heat-On heating mantle. The solvents (dichloromethane, methanol, 99.5% of purity) were obtained from commercial suppliers (TCI, Zwijndrecht, Belgium) and used without further purification unless otherwise stated. The P25 Aeroxide titanium(IV) oxide was purchased from Sigma-Aldrich, Taufkirchen, Germany. The other reagents (bisphenol A, methylene blue, and carbamazepine) were purchased from Merck, Darmstadt, Germany; TCI, Zwijndrecht, Belgium; and Fluorochem, Glossop, UK.
8
Pharmaceutical Stock Solution Preparation
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
A stock solution (1 g L -1 ) was prepared by weighing 0.1g each of the six selected pharmaceuticals (clofibric acid, diclofenac, carbamazepine, naproxen, ibuprofen, and ketoprofen) and dissolving the mixture in 10 mL of methanol (Merck Darmstadt, Germany), and analytical-grade substances in this regard were purchased from Sigma-Aldrich, Denmark.
9
Pharmaceutical Compound Characterization Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Active pharmaceutical ingredients of studied medicines, i.e., atenolol (Daroupakhsh, Iran), benzoic acid (Merck, Iran), carbamazepine (Arastoo, Iran), carvedilol (Salehan Shimi, Iran), Ibuprofen (Daana, Iran), ketoconazole (Arastoo, Iran), lamotrigine (Arastoo, Iran), phenothiazine (Merck, Germany), phenytoin (Alhavi, Iran), piroxicam (Zahravi, Iran) salicylic acid (Merck, Germany), sulfamethoxazole (Merck, Germany), and tadalafil (Osveh, Iran), were provided from pharmaceutical and chemical companies (Purity: > 99%). Ethanol (96% w/w) was purchased from Jahan Alcohol (Iran), and choline chloride (> 99%), glycerol (> 99%), and urea (> 99%) from Merck (Germany). Lab-made double distilled water was used for the preparation of solutions.
10
Analytical Workflow for Targeted Micropollutants
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Trimethoprim (TRM), metoprolol (MET), benzotriazole (BTA), carbamazepine (CBZ), caffeine (CAF), propranolol (PRO), sulfamethoxazole (SMZ), furosemide (FRS), mecoprop (MCPP), and diclofenac (DFC) were purchased from Sigma-Aldrich (U.S), and irbesartan (IBT) from TOKYO CHEMICAL INDUSTRY (Japan). Internal standards CAF-D9, SMX-D4, FRS-D5, MCPP-D6, DFC-D4 were purchased from LGC (Germany) and PRO-D7 from MERCK (the Netherlands). Details of these chemicals are presented in Table S1. Hydrogen chloride (HCl) was purchased from VWR chemicals (U.S). Methanol was bought from ACTU-ALL CHEMICALS (the Netherlands). Acetonitrile, ultrawater, and formic acid used in liquid chromatography-mass spectrometry (LC-MS) was purchased from ACTU-ALL CHEMICALS (The Netherlands).
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!