Mcf b65

Manufactured by Medtronic

The MCF B65 is a laboratory centrifuge device designed for general-purpose applications. It features a maximum speed of 6,500 rpm and a maximum relative centrifugal force (RCF) of 4,500 x g. The device can accommodate a variety of sample tube sizes and configurations. Detailed specifications and intended use information are available upon request.

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Lab products found in correlation

Magpro stimulator, by Medtronic (2 mentions)

2 protocols using mcf b65

Intermittent Theta Burst Stimulation Effects

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iTBS was delivered over the affected motor cortex “hot spot” for MEPs in the contralateral FDI muscle using a MagPro stimulator (Medtronic A/S Denmark) connected to a figure-of-eight coil (MCF B65). The magnetic stimulus had a biphasic waveform with a pulse width of about 280 μs and a maximum magnetic field strength of 1.5 T. The initial direction of the current induced in the brain was anterior to posterior. The stimulation intensity was defined in relation to the AMT evaluated using the MagPro stimulator. An intensity of 80% AMT was used. We applied the iTBS protocol in which 10 bursts of high frequency stimulation (3 pulses at 50 Hz) are delivered at 5 Hz every 10 s, for a total of 600 pulses (Huang et al., 2005 (link)). iTBS effects on both hemispheres were assessed by evaluating the changes of the RMT, AMT, and MEP amplitude stimulating the AH and UH, before and immediately after iTBS. MEP amplitude was evaluated as detailed above.

Di Lazzaro V., Pellegrino G., Di Pino G., Ranieri F., Lotti F., Florio L, & Capone F. (2016). Human Motor Cortex Functional Changes in Acute Stroke: Gender Effects. Frontiers in Neuroscience, 10, 10.

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Modulating Motor Cortex Excitability via iTBS

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iTBS was delivered over the affected motor cortex “hot spot” for MEPs in the contralateral FDI muscle using a MagPro stimulator (Medtronic A/S Denmark) connected to a figure-of-eight coil (MCF B65). The magnetic stimulus had a biphasic waveform with a pulse width of about 280 μs and a maximum magnetic field strength of 1.5 T. The initial direction of the current induced in the brain was anterior to posterior. The stimulation intensity was defined in relation to the AMT evaluated using the MagPro stimulator. An intensity of 80% AMT was used. We applied the iTBS protocol in which 10 bursts of high frequency stimulation (3 pulses at 50 Hz) are applied at 5 Hz every 10 s, for a total of 600 pulses [20 (link)].
MEP amplitude was evaluated before and immediately after iTBS using a stimulus intensity of 120% RMT with the muscle at rest. Subjects were given audio-visual feedback of their electromyographic (EMG) signal at high gain to assist them in maintaining complete relaxation; trials contaminated by EMG activity were discarded. Ten data sweeps were collected, and the mean peak-to-peak amplitude of the MEPs was calculated.

Di Lazzaro V., Pellegrino G., Di Pino G., Corbetto M., Ranieri F., Brunelli N., Paolucci M., Bucossi S., Ventriglia M.C., Brown P, & Capone F. (2014). Val66Met BDNF Gene Polymorphism Influences Human Motor Cortex Plasticity in Acute Stroke. Brain stimulation, 8(1), 92-96.

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