Fusion protein

Manufactured by Bausch & Lomb

Sourced in United States

Fusion Protein is a laboratory equipment used for the expression and purification of recombinant proteins. It combines two or more proteins or protein domains into a single polypeptide chain. Fusion Protein facilitates the isolation and characterization of target proteins by enhancing their solubility, stability, and detection.

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Lab products found in correlation

Tobramycin and dexamethasone eye drops, by Alcon (1 mentions) Proparacaine hydrochloride eye drops alcaine, by Alcon (1 mentions) Tobramycin, by Alcon (1 mentions) Dexamethasone (dex), by Alcon (1 mentions)

2 protocols using fusion protein

Penetrating Keratoplasty Surgical Protocol

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PKP was performed under general anesthesia with the anesthetist's assistance. The center of the host cornea was marked and then completely excised using a Barron vacuum trephine (Katena Products, Denville, NJ). The donor corneas were cut using a punch trephine on a Troutman guide (Medtronic Solan, Jacksonville, FL). All grafts had diameters between 7.0 and 8.0 mm. All grafts were closed with a continuous 24-bite running 10-0 nylon suture.
Postoperatively, patients received tobramycin and dexamethasone eye drops (Alcon Laboratories, Fort Worth, TX) 4 times per day for 3 months and recombinant bovine basic fibroblast growth factor (Fusion Protein, Bausch and Lomb, Rochester, NY) eye gel 3 times per day for 6 months. All eyes in the PKP group were treated with mannitol 1 time postoperatively.

Jin H., He M., Liu H., Zhong X., Wu J., Liu L., Ding H., Zhang C, & Zhong X. (2019). Small-Incision Femtosecond Laser–Assisted Intracorneal Concave Lenticule Implantation in Patients With Keratoconus. Cornea, 38(4), 446-453.

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Corneal Lenticule Implantation After SMILE

Cited 2 times

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All donor tissues were collected from the eye bank of the Hainan Eye Hospital in accordance with local guidelines (Hainan Entry-Exit Inspection and Quarantine Bureau of the People's Republic of China). Topical anaesthesia consisted of proparacaine hydrochloride eye drops (Alcaine; Alcon Laboratories, Fort Worth, TX). A myopic correction of −0.75 diopters (28 μm thickness) using a femtosecond laser system under SMILE treatment was performed on the recipient cornea, and the surgical incision was 2.5 mm long. The surgeon unfolded the lenticule with microforceps and created a “stromal pocket” at a depth of 160 μm from the cornea epithelium, followed by implantation of the lenticule into the “stromal pocket.” The surgical procedures were detailed in our previous studies [13 (link), 16 (link)]. Following the surgery, all patients received tobramycin and dexamethasone (Alcon Laboratories, US) eye drops 4 times per day for 2 weeks and recombinant bovine basic fibroblast growth factor (Fusion Protein, Bausch and Lomb, Rochester, NY) eye gel 3 times per day for 6 months.

Wei Q., Ding H., Nie K., Jin H., Zhong T., Yu H., Yang Z., Hu S., He L, & Zhong X. (2022). Long-Term Clinical Outcomes of Small-Incision Femtosecond Laser-Assisted Intracorneal Concave Lenticule Implantation in Patients with Keratoconus. Journal of Ophthalmology, 2022, 9774448.

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