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Pml rarα

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PML-RARα is a protein marker that is commonly used in research applications. It plays a role in the regulation of gene expression and cellular processes. PML-RARα is often studied in the context of certain types of cancer research.

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Lab products found in correlation

P53 antibody, by Thermo Fisher Scientific (3 mentions) Ki67 antibody, by Thermo Fisher Scientific (3 mentions) Confocal microscopy, by Olympus (3 mentions)

3 protocols using pml rarα

1

Immunocytochemical Analysis of NB4 Cells

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NB4 cells (1 × 105) were cultured in the presence or absence of CDDP and attached on poly‐l‐lysine coated slides. Immunocytochemistry of attached cells was performed using Ki67 antibody (dilution, 1:100) (cat# 33–4711) or p53 antibody (cat # 9282) and PML‐RARα (cat# ab43152) from Life Technology, Cell Signaling or Abcam company and imaged by confocal microscopy (Olympus Company), as described earlier.2
Kumar S, & Tchounwou P.B. (2022). p53 as a unique target of action of cisplatin in acute leukaemia cells. Journal of Cellular and Molecular Medicine, 26(17), 4727-4739.
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2

Immunocytochemical Analysis of APL Cells

Cited 1 time
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APL cells (1 × 105) were cultured in presence or absence of TX and attached on poly-L-lysine coated slides. Immunocytochemistry of attached cells were performed using Ki67 antibody (dilution, 1:100) (cat# 33-4711) [54 (link)] or p53 antibody (cat # 9282) and PML-RARα (cat# ab43152) from Life Technology, Cell Signaling or Abcam company and imaged by confocal microscopy (Olympus Company, Center valley, PA) as described earlier [2 (link)].
Kumar S., Brown A, & Tchounwou P.B. (2018). Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells. Oncotarget, 9(69), 33138-33148.
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3

Immunocytochemistry of Bone Marrow Cells

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APL bone marrow cells (1x105) were cultured in presence or absence of TX and attached on poly-L-lysine coated slides. Immunocytochemistry of attached cells was performed using Ki67 antibody (dilution, 1:100) (cat# 33-4711) or p53 antibody (cat # 9282) and PML-RARα (cat# ab43152) from Life Technology, Cell Signaling or Abcam company and imaged by confocal microscopy (Olympus Company, Center valley, PA) as previously described 2 (link).
Kumar S, & Tchounwou P.B. (2020). Trisenox Disrupts MDM2-DAXX-HAUSP Complex and Induces Apoptosis in a Mouse Model of Acute Leukemia. Journal of Cancer, 11(15), 4373-4383.
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