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Signa 3.0t mr scanner

Manufactured by GE Healthcare
Sourced in United States

The Signa 3.0T MR scanner is a magnetic resonance imaging (MRI) system designed and manufactured by GE Healthcare. It operates at a magnetic field strength of 3.0 Tesla, providing high-quality imaging capabilities for medical diagnostic and research applications.

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3 protocols using signa 3.0t mr scanner

1

MRI Characterization of Tumor Xenograft

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Imaging was performed three weeks after tumor implantation. MR imaging was performed on a Signa 3.0T MR scanner (General Electric Healthcare, Milwaukee, USA) using an 8-channel rabbit coil (Suzhou Zhongzhi Medical Technology Co., Ltd.). Protocols include pre-contrast axial, sagittal and coronal T1-weighted spin-echo sequences (TR/TE, 820/9.369; Fov, 20 cm; Nex 4), pre-contrast sagittal T2-weighted fast spin echo sequences (TR = 2940msec, TE = 85.816msec; Fov = 20 cm; Nex = 4), sagittal short time inversion recovery (STIR) sequences (TR = 3800 msec, TE = 38.92 msec; Inversion time = 180 msec; Fov = 20 cm; Nex = 4), with slice thickness 3 mm and interval 1 mm. Pre- and post-contrast sagittal fast spoiled gradient recalled echo sequences (TR = 6.5 msec, TE = 1.4 msec; Fov = 20 cm; Nex = 1; Matrix = 192 × 168; Slice thickness = 3 mm; Interval = 1 mm; Flip angle = 12°) were performed. Fifty phases were scanned. After the second phases, 1 ml/kg Gd-DTPA (Magnevist; Bayer Schering Pharma AG, Berlin, Germany) was administered followed by 10 ml saline flush injected at a rate of 1.5 ml/s with an automated injector. Pre-contrast T1 mapping images with multiple flip angles (8°,10°,12°) were obtained.
After scanning, data were transferred automatically to the workstation. Omni Kinetics software was used to quantitatively analysis. The femoral artery was manually labeled as the input artery.
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2

Neuroimaging of Antipsychotic-Naive Patients

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Patients were scanned after written informed consent was obtained, but before treatment initiation; in all cases, this was on the same day of initial assessment, along with other laboratory assessments required for routine clinical care. Patients were not included in the study if any exposure to antipsychotics took place before the scanning. 206 patients and 170 HC were scanned on a Signa 3.0-T MR scanner [General Electric (GE), Medical Systems, USA] using an eight-channel phased-array head coil in the Department of Radiology at West China Hospital. The scan parameters are listed in the Supplementary Methods. 137 patients and 172 HC were scanned on a 3.0 T MR scanner (Philips Achieva, Amsterdam, the Netherlands) using an eight-channel phased-array head coil in the department of Radiology at West China Hospital Tibet People's Government in Chengdu Office Branch. The data from the 2 scanners (datasets 1 and 2 respectively) were combined for aggregated analysis; see online supplementary materials for scanner-related variations.
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3

Multimodal Integration of EEG and fMRI

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Data acquisition and preprocessing. EEG data were recorded using a Brain Products MR-compatible EEG system. Brain Vision Analyzer 2.0 was used to remove MR scanner artefacts in the EEG. fMRI data were collected using a General Electric Signa 3.0T MR scanner using a GE-EPI fMRI sequence. Two resting-state fMRI (rsfMRI) with opened and closed eyes were acquired. Standard preprocessing was performed on MR images using FSL v4.1.8.
Data analyses, i) RS functional Networks (RSN) were identified after applying an ICA approach. Each RSN characteristic time-course for the opened and closed rsfMRI series was analyzed to achieve the correlation degree among RSNs. ii) Three GLM designs per fMRI series were computed using the EEG power time series (one EEG power value per fMRI volume convolved with the canonical HRF) regressors for three bands of interest -alpha, theta and beta bands -[2]
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