Spss for windows software package version 20

SPSS for Windows software package version 20.0 (SPSS Inc., Chicago, IL, USA) was used to analysis the data. Genotypic association were provided by the SNPstats online analysis software including the codominant, dominant, recessive, and overdominant genetic models [27 (link)], and the Hardy-Weinberg equilibrium was evaluated by chi-squared test. The level of significance was set at P < 0.05. The effects of different genotypes and alleles were evaluated by odds ratio (OR) and respective 95% confidence intervals (95% CI). Kaplan-Meier plots and the log-rank test were used to estimate the relationships of AXIN1 genotypes with patients' outcomes (recurrence and death). Considering age at first diagnosis, sex, smoking status, tumor grade, and clinical stage, Cox regression analysis model was used for multivariate survival analysis.

Continuous and categorical variables were presented as median (IQR) and n (%), respectively. SPSS for Windows software package, version 20.0 (SPSS Inc, Chicago, IL) was used. Mann-Whitney U test or χ² test was used to compare differences between the normal CT group and the abnormal CT group. To explore the risk factors associated with abnormal CT findings, univariate and multivariate logistic regression models were used. By referring to the relevant literature, we selected age, gender, body temperature, underlying diseases, symptoms, white blood cell count, neutrophil count, lymphocyte count, and C-reactive protein as variables for stepwise logistic regression analysis (20 (link)). At the same time, parameters of odds ratios that were difficult to estimate were excluded due to the small number of cases as well as the parameters that had collinearity with the underlying disease. A P-value < 0.05 was considered statistically significant.

Statistical analyses were performed to compare the CT findings in infections by the 3 different viruses. The SPSS for Windows software package, version 20.0 (SPSS Inc, Chicago, IL) was used. Categorical variables were compared using the χ² or Fisher exact test, and continuous variables were compared using the Mann–Whitney U test. A P-value < 0.05 were considered statistically significant.