Clinicopathological and Inflammation Markers in Colorectal Cancer

Clinicopathological features included age, sex, tumor location (tumor distance from the anal verge), adjuvant chemotherapy, tumor grade, tumor stage, vascular invasion and perineural invasion. As systemic inflammation markers, the blood-based NLR was calculated based on pre-operative data. Blood-based NLR = blood-based total neutrophil count (10⁹/L)/ blood-based total lymphocyte count (10⁹/L). Following previously established procedures^{6 (link)}, we meticulously reviewed all hematoxylin and eosin-stained sections, selected representative sections, and cut sections into 4-μm-thick slices. The MoticEasyScan Infinity was used to scan all hematoxylin and eosin-stained sections, and Motic DSAssistant was used to analyze.