pMSCV-Ires-GFP, pMSCV-FLT3WT-Ires-GFP, and pMSCV-FLT3ITD-Ires-GFP were described previously.21 (link) Ruxolitinib and pacritinib were purchased from Chemietech Inc. Quizartinib, sorafenib, midostaurin, lestaurtinib, crenolanib, gilteritinib, and momelotinib were purchased from AdooQ Bioscience.
Protocol detail
Viral Transduction Constructs for FLT3 Signaling
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Crenolanib
Gilteritinib
Ires
Lestaurtinib
Midostaurin
Momelotinib
Pacritinib
Quizartinib
Ruxolitinib
Sorafenib
Corresponding Organization :
Other organizations : Cincinnati Children's Hospital Medical Center, Pediatrics and Genetics, University of Cincinnati
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Variable analysis
independent variables
- PMSCV-Ires-GFP
- PMSCV-FLT3WT-Ires-GFP
- PMSCV-FLT3ITD-Ires-GFP
- Ruxolitinib
- Pacritinib
- Quizartinib
- Sorafenib
- Midostaurin
- Lestaurtinib
- Crenolanib
- Gilteritinib
- Momelotinib
- Not explicitly mentioned
- Not explicitly mentioned
- No positive or negative controls were specified by the authors.
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