Sleep Fragmentation in Alzheimer's Mice
Corresponding Organization :
Other organizations : University of Turin, Azienda Ospedaliera Citta' della Salute e della Scienza di Torino, Università di Camerino
Variable analysis
- Sleep fragmentation protocol: 3 min OFF/10 s ON
- Duration of sleep fragmentation: 30 days
- Sleep-wake cycle: Measured by electroencephalography (EEG) and electromyographic (EMG) recording on the last day of the experiment
- Mouse genotypes: Wild type (wt) and 5xFAD
- Mouse age: 2-month-old and 6-month-old
- Environmental conditions: Kept constant between fragmented and non-fragmented groups
- Duration of observation: 24 hours, based on the light/dark cycle
- Non-fragmented groups: 2-month-old wt (n = 11), 2-month-old 5xFAD (n = 11), and 6-month-old 5xFAD (n = 4) mice
- Not specified
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