In order to evaluate the predictive performance of ML models about adverse pregnancy outcomes, we grouped the women as following: (1) Adverse Group (n = 22): individuals associated with adverse pregnancy outcomes; (2) Positive Group (n = 29): individuals associated with satisfactory pregnancy outcomes (having no adverse outcomes).
Adverse pregnancy outcomes including one or more of the following: (1) fetal death after 13 weeks’ gestation excluded chromosomal abnormalities, anatomical malformation, or congenital infection [11 (link)]; (2) early neonatal death (death before 8 days of age) due to complications of prematurity and/or placental insufficiency [12 (link)]; (3) preterm delivery at less than 37 weeks due to gestational hypertension, preeclampsia, HELLP syndrome, placental insufficiency, placenta abruption or premature rupture of membranes [12 (link)]; (4) SGA neonate (<10th percentile) [12 (link)]; (5) fetal distress which was certified by pathological type observed in the cardiotocography [13 (link)]; (6) the SLE pregnancy disease activity index (SLEPDAI) was more than 4 [14 (link)].
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