MRI Imaging Protocol for 3T Brain Scans

MRI scanning was performed on a GE × 750 3 T scanner (General Electric, Waukesha, WI, USA) with an eight-channel head coil and parallel imaging with the Array Spatial Sensitivity Encoding Technique. A T1-weighted volume scan was acquired in the axial plane with a 3D fast spoiled gradient-echo sequence using the following parameters: inversion time (TI) = 450 ms; repetition time (TR) = 8.2 ms; echo time (TE) = 3.2 ms; flip angle = 12°; acquisition matrix = 256 mm × 256 mm, field of view (FOV) = 256 mm; slice thickness = 1.0 mm, no gap, yielding a voxel resolution of 1 mm isometric. A 3D T2 FLAIR sequence was acquired in the sagittal plane using the following parameters: TI = 1868 ms; TR = 6000 ms; TE = 123 ms; flip angle = 90°; acquisition matrix = 256 mm × 256 mm, FOV = 256 mm; slice thickness = 2.0 mm, no gap, yielding a voxel resolution of 1 mm × 1 mm × 2 mm. Additional details have been previously described [6 (link), 7 (link)].

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Vesperman C.J., Pozorski V., Dougherty R.J., Law L.L., Boots E., Oh J.M., Gallagher C.L., Carlsson C.M., Rowley H.A., Ma Y., Bendlin B.B., Asthana S., Sager M.A., Hermann B.P., Johnson S.C., Cook D.B, & Okonkwo O.C. (2018). Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort. Alzheimer's Research & Therapy, 10, 97.

Publication 2018

× 750 3 T scanner eight-channel head coil

Echo Electric Head Inversion Scan Sensitivity

Corresponding Organization :

Other organizations : William S. Middleton Memorial Veterans Hospital, Geriatric Research Education and Clinical Center, University of Wisconsin–Madison, University of Illinois at Chicago

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Variable analysis

independent variables

Magnetic field strength (3 T)

dependent variables

T1-weighted volume scan
3D T2 FLAIR sequence

control variables

GE × 750 scanner
Eight-channel head coil
Parallel imaging with the Array Spatial Sensitivity Encoding Technique
T1-weighted volume scan parameters (TI = 450 ms, TR = 8.2 ms, TE = 3.2 ms, flip angle = 12°, acquisition matrix = 256 mm × 256 mm, FOV = 256 mm, slice thickness = 1.0 mm, no gap, voxel resolution = 1 mm isometric)
3D T2 FLAIR sequence parameters (TI = 1868 ms, TR = 6000 ms, TE = 123 ms, flip angle = 90°, acquisition matrix = 256 mm × 256 mm, FOV = 256 mm, slice thickness = 2.0 mm, no gap, voxel resolution = 1 mm × 1 mm × 2 mm)

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