Cardiac Imaging Evaluation Protocol

Accuracy of the echocardiographic methods was defined by agreement according to CMR^{15 (link)–17 (link)}. CMR images were obtained using a 1.5 Tesla system (GE Optima MR450W, GE Healthcare, Waukesha, WI) with a phased-array cardiac coil. Cine images were acquired during breath-hold using a steady-state free precession cine sequence with retrospective gating^{18 (link)}. Slice thickness 8 mm, no gaps, field of view 300–360 mm, 25 phases/cycle. Analysis was performed using CVI42 (Circle Cardiovascular Imaging Inc., Version 5.6.5, Canada). End-diastole was defined as for echocardiography. Endocardium and epicardium were manually delineated in the short-axis-stack, papillary muscles were considered part of the LV volume. The subjects were classified in four groups according to age, gender and indexed values^{19 (link)} of the EDV_ENDO and LVM^{20 (link)}; normal, dilatation, hypertrophy, dilatation and hypertrophy.

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Kristensen C.B., Myhr K.A., Grund F.F., Vejlstrup N., Hassager C., Mattu R, & Mogelvang R. (2022). A new method to quantify left ventricular mass by 2D echocardiography. Scientific Reports, 12, 9980.

Publication 2022

GE Optima MR450W CVI42

Axis Cardiac Cardiovascular Diastole Dilatation Echocardiography Endocardium Epicardium Hypertrophy Papillary muscles

Corresponding Organization : Rigshospitalet

Other organizations : Kettering General Hospital, University of Copenhagen

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Variable analysis

independent variables

Gender

dependent variables

End-diastolic volume (EDV_ENDO)
Left ventricular mass (LVM)

control variables

CMR imaging using a 1.5 Tesla system (GE Optima MR450W, GE Healthcare, Waukesha, WI) with a phased-array cardiac coil
Cine images acquired during breath-hold using a steady-state free precession cine sequence with retrospective gating
Slice thickness 8 mm, no gaps, field of view 300–360 mm, 25 phases/cycle
Analysis performed using CVI42 (Circle Cardiovascular Imaging Inc., Version 5.6.5, Canada)
End-diastole defined as for echocardiography
Endocardium and epicardium manually delineated in the short-axis-stack, papillary muscles considered part of the LV volume

positive controls

CMR as the reference standard for accuracy of echocardiographic methods (based on references 15-17)

negative controls

Not mentioned

Annotations

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