3D high-resolution T1weighted MR imaging data (MPRAGE) were obtained from 110 HS (mean age 34.9 years, median age 30.9 years, range 18–72 years, SD 12.8, 53.6% women) on 1.5T (45%) and 3T (55%) scanners with two different protocols, respectively.
Briefly, acquisition parameters for the 1.5T Magnetom Avanto scanner (Siemens Healthineers, Erlangen, Germany) were TR = 2,080 ms, TI = 1,100 ms, TE = 3 ms, α = 15°, spatial resolution of 0.98 × 0.98 × 1 mm3 (Bendfeldt et al., 2009 (link); Weier et al., 2014 (link)) and TR = 2,700 ms, TI = 950 ms, TE = 5 ms, α = 8°, spatial resolution of 1 × 1 × 1 mm3. For the 3T Prisma scanner (Siemens Healthineers, Erlangen, Germany) acquisition parameters were TR = 1,680 ms, TI = 900 ms, TE = 2.5 ms, α = 8°, spatial resolution of 1 × 1 × 1 mm3 and TR = 2,300 ms, TI = 900 ms, TE = 3 ms, α = 9°, spatial resolution of 1 × 1 × 1 mm3, acceleration factor 2.
Written informed consent was obtained from all participants mentioned above.
All brainstem segmentations were visually inspected for anatomic accuracy.
Briefly, acquisition parameters for the 1.5T Magnetom Avanto scanner (Siemens Healthineers, Erlangen, Germany) were TR = 2,080 ms, TI = 1,100 ms, TE = 3 ms, α = 15°, spatial resolution of 0.98 × 0.98 × 1 mm3 (Bendfeldt et al., 2009 (link); Weier et al., 2014 (link)) and TR = 2,700 ms, TI = 950 ms, TE = 5 ms, α = 8°, spatial resolution of 1 × 1 × 1 mm3. For the 3T Prisma scanner (Siemens Healthineers, Erlangen, Germany) acquisition parameters were TR = 1,680 ms, TI = 900 ms, TE = 2.5 ms, α = 8°, spatial resolution of 1 × 1 × 1 mm3 and TR = 2,300 ms, TI = 900 ms, TE = 3 ms, α = 9°, spatial resolution of 1 × 1 × 1 mm3, acceleration factor 2.
Written informed consent was obtained from all participants mentioned above.
All brainstem segmentations were visually inspected for anatomic accuracy.
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