Literature searches were performed by meeting participants to identify new data in English language papers published between January 2014 and October 2019, and indexed in PubMed. Search terms included “acromegaly” and terms associated with each topic, including “biochemical control”, “tumor volume”, “clinical symptoms”, “side effects”, “neurosurgery”, “radiother-apy”, “somatostatin analogue”, “somatostatin receptor ligand”, “pegvisomant”, “morbidity”, “mortality”, “quality of life”,and “guidelines”. After brief plenary overviews on the state of the art for each topic, participants were divided into breakout groups for further analysis of the assigned topics and subsequently reported their conclusions to the whole group. Consensus recommendations were produced based on speaker presentations, subgroup discussions, and reports. After the meeting, the Scientific Committee graded the evidence supporting the recommendations, and then graded the consensus recommendations on the basis of the quality of evidence (Table 2). Final graded consensus recommendations were approved by all meeting participants.
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Giustina A., Barkhoudarian G., Beckers A., Ben-Shlomo A., Biermasz N., Biller B., Boguszewski C., Bolanowski M., Bollerslev J., Bonert V., Bronstein M.D., Buchfelder M., Casanueva F., Chanson P., Clemmons D., Fleseriu M., Formenti A.M., Freda P., Gadelha M., Geer E., Gurnell M., Heaney A.P., Ho K.K., Ioachimescu A.G., Lamberts S., Laws E., Losa M., Maffei P., Mamelak A., Mercado M., Molitch M., Mortini P., Pereira A.M., Petersenn S., Post K., Puig-Domingo M., Salvatori R., Samson S.L., Shimon I., Strasburger C., Swearingen B., Trainer P., Vance M.L., Wass J., Wierman M.E., Yuen K.C., Zatelli M.C, & Melmed S. (2020). Multidisciplinary management of acromegaly: A consensus. Reviews in endocrine & metabolic disorders, 21(4), 667-678.
Other organizations :
IRCCS Ospedale San Raffaele, Pacific Heart Institute, University of Liège, Cedars-Sinai Medical Center, Leiden University Medical Center, Harvard University, Massachusetts General Hospital, Universidade Federal do Paraná, Wroclaw Medical University, University of Oslo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Universitätsklinikum Erlangen, Universidade de Santiago de Compostela, Assistance Publique – Hôpitaux de Paris, Inserm, Université Paris-Sud, Université Paris-Saclay, University of North Carolina at Chapel Hill, Oregon Health & Science University, Neurological Surgery, Columbia University, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Memorial Sloan Kettering Cancer Center, Wellcome/MRC Institute of Metabolic Science, Addenbrooke's Hospital, Wellcome Trust, University of Cambridge, University of California, Los Angeles, Garvan Institute of Medical Research, UNSW Sydney, St Vincent's Hospital, Emory University, Erasmus MC, Brigham and Women's Hospital, San Raffaele University of Rome, University of Padua, Hospital de Especialidades, Universidad Nacional Autónoma de México, Centro Medico Nacional Siglo XXI, Northwestern University, Mount Sinai Health System, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Johns Hopkins University, Baylor College of Medicine, Rabin Medical Center, Charité - Universitätsmedizin Berlin, Manchester Academic Health Science Centre, University of Manchester, The Christie NHS Foundation Trust, University of Virginia, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, University of Colorado Anschutz Medical Campus, Barrow Neurological Institute, University of Arizona, University of Ferrara
Literature searches performed by meeting participants
Search terms used, including "acromegaly" and associated terms
dependent variables
New data in English language papers published between January 2014 and October 2019
Biochemical control
Tumor volume
Clinical symptoms
Side effects
Neurosurgery
Radiotherapy
Somatostatin analogue
Somatostatin receptor ligand
Pegvisomant
Morbidity
Mortality
Quality of life
control variables
Papers indexed in PubMed
Annotations
Based on most similar protocols
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As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.
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