To a solution of quaternary ammonium salt (0.001 mmol, 1 mol%) in mesitylene (1.0 mL) was added nitromethane (2.0 equiv.) and base (0.1 equiv.). After stirring for 5 min, the corresponding N-Boc trifluoromethyl ketimine (0.1 mmol) was added. The reaction was monitored by TLC until it was completed, and the residue was purified by flash silica gel column chromatography to give trifluoromethyl β-nitroamines.
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