Genetically Modified Mouse Models

Mouse: C57BL/6J (Charles River laboratories), Mouse: Alb-CreERT²/E4BP4 ^hep−/− [Mouse Clinical Institute (ICS)], Mouse: Alb-CreERT²/BMAL1 ^hep−/− [Jackson laboratories B6.129S4 (Cg)-Arntltm1Weit/J], Mouse: Alb-CreERT²/RevErbα ^hep−/− [Mouse Clinical Institute (ICS)], and Mouse: Alb-CreERT²/RORα/RORγ ^hep−/− [Mouse Clinical Institute (ICS)].

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Misra N., Damara M., Ye T, & Chambon P. (2023). The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene. Proceedings of the National Academy of Sciences of the United States of America, 120(8), e2214062120.

Publication 2023

C57BL/6J

Mouse River Rorα

Corresponding Organization :

Other organizations : Institut de génétique et de biologie moléculaire et cellulaire, Inserm, Centre National de la Recherche Scientifique, Université de Strasbourg, Collège de France

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Variable analysis

independent variables

Mouse: C57BL/6J (Charles River laboratories)
Mouse: Alb-CreERT2/E4BP4 hep−/− [Mouse Clinical Institute (ICS)]
Mouse: Alb-CreERT2/BMAL1 hep−/− [Jackson laboratories B6.129S4 (Cg)-Arntltm1Weit/J]
Mouse: Alb-CreERT2/RevErbα hep−/− [Mouse Clinical Institute (ICS)]
Mouse: Alb-CreERT2/RORα/RORγ hep−/− [Mouse Clinical Institute (ICS)]

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

controls

Positive control: Not mentioned
Negative control: Not mentioned

Annotations

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